3-Chloro-5-(trifluoromethyl)picolinic acid
- CAS No.80194-68-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Chloro-5-(trifluoromethyl)picolinic acid (CAS 80194-68-9), a key pyridine-based intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
Request Bulk PricingProduct Technical Details
Product Overview
3-Chloro-5-(trifluoromethyl)picolinic acid is a high-value pyridine-derived carboxylic acid widely employed as a versatile building block in complex organic synthesis. With its unique combination of electron-withdrawing trifluoromethyl and chlorine substituents at strategic positions on the pyridine ring, this compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and innovative crop protection agents. Our product is manufactured under stringent quality control protocols to ensure consistent performance in demanding synthetic applications.
Specifications
| Molecular Formula | C7H3ClF3NO2 |
|---|---|
| Molecular Weight | 225.552 g/mol |
| CAS Number | 80194-68-9 |
| Appearance | White to cream powder |
| Assay | ≥98.0% |
| Melting Point | 141–143°C |
| Boiling Point | 269.6 ± 40.0 °C at 760 mmHg |
| Density | 1.6 ± 0.1 g/cm³ |
| Flash Point | 116.9 ± 27.3 °C |
Industrial Applications
This compound is primarily utilized as a specialty intermediate in multi-step syntheses requiring regioselective functionalization of heterocyclic scaffolds. Key application areas include:
- Pharmaceutical research for constructing novel neurological and metabolic therapeutics
- Agrochemical innovation in the design of next-generation herbicides and insecticides
- Material science projects involving fluorinated heteroaromatic systems
Its robust reactivity profile enables efficient derivatization via esterification, amidation, cross-coupling, and nucleophilic aromatic substitution reactions.
Handling and Storage
Store in a cool, dry, and well-ventilated area away from incompatible materials. Keep container tightly closed when not in use. Standard industrial hygiene practices should be followed during handling. Packaging is typically provided in 25 kg fiber drums, with custom packaging options available upon request.
