3-Chloroanisole
- CAS No.2845-89-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Chloroanisole (CAS 2845-89-8) is a vital organic synthesis intermediate. Ideal for pharmaceutical and agrochemical manufacturing with ≥98.0% assay.
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Product Overview
3-Chloroanisole, also known by its systematic name 1-chloro-3-methoxybenzene, stands as a critical aromatic ether intermediate within the modern chemical industry. This colorless transparent liquid is characterized by its distinct chemical stability and reactivity profile, making it an indispensable building block for complex organic synthesis pathways. Our facility specializes in the production of high-purity grades, ensuring that every batch meets rigorous international standards for pharmaceutical and agrochemical development. The compound features a methoxy group positioned meta to the chlorine atom on the benzene ring, which dictates its specific nucleophilic substitution behaviors. We employ advanced distillation techniques to remove isomeric impurities, guaranteeing the structural integrity required for sensitive catalytic processes.
As a leading global manufacturer, we understand that the purity of raw materials directly impacts the yield and safety of downstream processes. Therefore, our 3-Chloroanisole is manufactured under strict quality control protocols, achieving an assay of ≥98.0%. This level of purity minimizes impurities that could interfere with catalytic reactions or final product crystallization. Whether used in laboratory-scale research or industrial-scale production, consistency is key to our value proposition. We maintain full traceability from raw material sourcing to final packaging, ensuring compliance with global regulatory frameworks.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 2845-89-8 |
| Molecular Formula | C7H7ClO |
| Molecular Weight | 142.583 |
| Appearance | Colorless transparent liquid |
| Assay | ≥98.0% |
| Boiling Point | 197.5±0.0 °C at 760 mmHg |
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 73.3±0.0 °C |
| Refractive Index | 1.515 |
Industrial Applications
The primary utility of 3-Chloroanisole lies in its role as a versatile intermediate for organic synthesis. It is frequently employed in the construction of pharmaceutical active ingredients where the meta-substitution pattern is required for biological activity. Additionally, this chemical serves as a precursor in the agrochemical sector for developing novel herbicides and pesticides. The chlorine atom provides a handle for cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, while the methoxy group can act as a protecting group or be demethylated to reveal a phenolic functionality later in the synthesis tree.
Researchers value this compound for its predictable reactivity and solubility profile in common organic solvents. It is also utilized in the fragrance and flavor industry, although less commonly than in pharmaceuticals, due to its aromatic characteristics. Our supply chain supports both R and D departments requiring small quantities for method development and production plants needing bulk volumes for continuous manufacturing processes. The stability of the ether linkage allows for harsh reaction conditions without degradation, making it suitable for multi-step synthesis routes where intermediate isolation is necessary.
Safety, Storage, and Logistics
Proper handling of 3-Chloroanisole is essential to maintain product integrity and ensure workplace safety. The material should be stored in a cool, ventilated place away from direct sunlight and sources of ignition, given its flash point of 73.3°C. Containers must remain tightly sealed to prevent moisture absorption or contamination from atmospheric particulates. We recommend using standard personal protective equipment, including chemical-resistant gloves and safety goggles, during transfer operations. In the event of a spill, absorb with inert material and dispose of according to local environmental regulations. Our team provides comprehensive safety training documentation upon request to ensure your personnel are fully informed.
For logistics, we offer flexible packing options to suit various customer requirements. The standard packaging is 200 kg per drum, which optimizes shipping efficiency and reduces freight costs for large orders. However, we can accommodate smaller containers or specialized isotainers upon request. Every shipment is accompanied by a comprehensive Certificate of Analysis and Safety Data Sheet to facilitate regulatory compliance and smooth customs clearance globally. Our commitment extends beyond mere supply; we provide technical support to ensure the material integrates seamlessly into your specific manufacturing workflow.
