Intermediates

3-Chlorophenylboronic acid

  • CAS No.63503-60-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 3-Chlorophenylboronic acid (CAS 63503-60-6) designed for pharmaceutical synthesis. High purity ≥98% ensures reliable reaction yields for advanced API manufacturing.

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Product Technical Details

Product Overview

3-Chlorophenylboronic acid is a highly valued organoboron compound that serves as a fundamental building block in modern organic synthesis and medicinal chemistry. Characterized by its stable boronic acid functional group attached to a chlorinated phenyl ring, this chemical reagent is essential for facilitating carbon-carbon bond formation reactions. Our manufacturing process ensures exceptional consistency and purity, making it an ideal choice for research laboratories and industrial-scale production facilities focused on complex molecule assembly.

As a key intermediate, this compound plays a pivotal role in the development of advanced pharmaceutical agents and fine chemicals. The presence of the chlorine substituent at the meta position provides specific reactivity profiles that are crucial for selective coupling reactions. We adhere to strict quality control protocols to guarantee that every batch meets rigorous international standards for chemical integrity and performance.

Technical Specifications

ParameterValue
CAS Number63503-60-6
Molecular FormulaC6H6BClO2
Molecular Weight156.38 g/mol
AppearanceWhite to light yellow crystalline powder
Assay (Purity)≥98.0%
Water Content≤0.50%
Melting Point185-189 °C
Density1.32 g/cm3
Boiling Point311.4 °C at 760 mmHg
Flash Point142.1 °C

Industrial Applications

This boronic acid derivative is extensively utilized in Suzuki-Miyaura cross-coupling reactions, which are foundational in the synthesis of biaryls and heterocycles. Its high purity level minimizes side reactions and catalyst poisoning, thereby enhancing overall process efficiency. In the pharmaceutical sector, it is employed as a critical precursor for constructing complex molecular frameworks required for novel therapeutic compounds. Additionally, it finds applications in materials science for the development of specialized polymers and organic electronic materials.

The versatility of 3-Chlorophenylboronic acid allows chemists to introduce specific functional groups with high precision. Whether used in small-scale discovery chemistry or large-scale commercial manufacturing, this reagent provides reliable performance. Our technical team supports customers with detailed synthesis routes and application guidance to optimize usage in specific chemical processes.

Quality Assurance and Safety

Quality is paramount in our production facility. Each batch undergoes comprehensive analytical testing using HPLC and NMR spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with regulatory requirements. We maintain a robust quality management system to prevent contamination and ensure product stability during storage and transit.

Regarding safety, this substance is classified under transport hazard class 3 with UN number 3271. It should be handled in accordance with standard laboratory safety practices. Proper personal protective equipment, including gloves and eye protection, is recommended during handling. The material must be stored in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents. Containers should remain tightly closed to prevent moisture absorption, which can affect product quality over time.

Packaging and Logistics

We offer flexible packaging solutions to meet diverse customer needs. The standard package consists of 25kg drums, which are designed for safe and efficient global shipping. Custom packaging configurations are available upon request to accommodate specific logistical requirements. Our supply chain team ensures timely delivery worldwide, maintaining the integrity of the product throughout the transportation process. For bulk orders, competitive pricing structures are available to support large-scale industrial projects.