Intermediates

3-Dimethylaminopropylchloride Hydrochloride

  • CAS No.5407-04-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 3-Dimethylaminopropylchloride Hydrochloride (CAS 5407-04-5) designed for pharmaceutical synthesis. A critical intermediate for antidepressant APIs like Citalopram.

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Product Technical Details

Product Overview

3-Dimethylaminopropylchloride Hydrochloride is a high-performance organic intermediate essential for the synthesis of complex pharmaceutical active ingredients. As a specialized amine hydrochloride salt, this compound serves as a foundational building block in the production of selective serotonin reuptake inhibitors (SSRIs). Our manufacturing process ensures exceptional consistency and purity, meeting the rigorous demands of modern medicinal chemistry and large-scale API production.

This chemical is characterized by its stability and reactivity, making it an ideal candidate for nucleophilic substitution reactions required in multi-step synthesis pathways. We prioritize quality control at every stage, from raw material sourcing to final packaging, to guarantee that each batch complies with international pharmaceutical standards.

Key Specifications

ParameterSpecification
CAS Number5407-04-5
Molecular FormulaC5H13Cl2N
Molecular Weight158.069
AppearanceWhite powder
Assay≥98.0%
Melting Point187-190 °C
Boiling Point130.7 °C at 760mmHg
Flash Point32.8 °C

Industrial Applications

The primary application of 3-Dimethylaminopropylchloride Hydrochloride lies in the pharmaceutical sector, specifically as a key intermediate in the manufacturing of antidepressant medications. It is critically used in the synthesis pathways for Citalopram and Escitalopram, which are widely prescribed APIs for treating depression and anxiety disorders. The high purity of our product ensures minimal impurity carryover into the final drug substance, facilitating smoother regulatory approval processes.

Beyond antidepressant synthesis, this compound serves as a versatile reagent in organic chemistry laboratories for introducing dimethylaminopropyl groups into various molecular structures. Its reliability supports research and development efforts aimed at creating new therapeutic agents.

  • Essential intermediate for SSRI antidepressant APIs
  • Supports scalable manufacturing processes
  • Compatible with standard organic synthesis protocols
  • Ensures high yield in downstream reactions

Quality Assurance and Storage

We maintain a robust quality management system to ensure product integrity. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing physical and chemical properties. To maintain stability, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper handling procedures are recommended to ensure safety during industrial use.

Our packaging options include 25 kg drums, with flexibility to accommodate specific customer requirements for bulk orders. We are committed to providing reliable global supply chain solutions for pharmaceutical manufacturers and chemical distributors seeking dependable raw materials.