Intermediates

3-Fluoro-2-methylbenzaldehyde

  • CAS No.147624-13-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Fluoro-2-methylbenzaldehyde (CAS 147624-13-3) designed for pharmaceutical synthesis and organic research applications.

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Product Technical Details

Product Overview

3-Fluoro-2-methylbenzaldehyde (CAS 147624-13-3) represents a critical fluorinated building block within the realm of advanced organic synthesis and medicinal chemistry. As a specialized aromatic aldehyde, this compound serves as an essential intermediate for constructing complex molecular architectures. Our manufacturing process ensures high purity levels, making it suitable for demanding research and development applications in the pharmaceutical sector. The strategic placement of the fluorine atom enhances the chemical stability and reactivity profile required for modern drug discovery pipelines.

The introduction of a fluorine atom at the meta-position relative to the aldehyde group, combined with an ortho-methyl substituent, imparts unique electronic and steric properties to the benzene ring. These characteristics are highly valued in drug design, where fluorination often enhances metabolic stability and bioavailability of the final active pharmaceutical ingredients. We supply this material with rigorous quality controls to support seamless integration into your synthesis workflows.

Technical Specifications

We adhere to strict quality control protocols to guarantee consistency across batches. The following table outlines the key physical and chemical parameters verified during our quality assurance process. Each batch is tested to ensure compliance with international standards for fine chemicals.

Parameter Value
CAS Number 147624-13-3
Molecular Formula C8H7FO
Molecular Weight 138.14 g/mol
Purity ≥99.0%
Appearance Colorless to pale yellow solid
Density 1.16 g/cm3
Boiling Point 92-93 °C
Flash Point 81 °C
Refractive Index 1.526

Industrial Applications

This fluorinated aldehyde is primarily utilized as a reagent in the synthesis of biologically active compounds. Notable applications include the preparation of resveratrol derivatives incorporating a curcumin moiety, which are investigated for their potential as antitubulin agents. Furthermore, it plays a pivotal role in the construction of indenopyrazine dicarbonitriles, which act as inhibitors of deubiquitinating enzymes. These pathways highlight its versatility in developing potential therapeutic candidates and other research chemicals.

  • Synthesis of heterocyclic compounds for drug discovery.
  • Development of kinase inhibitors and enzyme modulators.
  • Production of fluorinated pharmaceutical intermediates.
  • Research into enzyme inhibition mechanisms and biological pathways.

Quality Assurance and Packaging

Every shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified standards. We offer flexible packaging solutions, typically supplying 25 kg per drum, though custom packaging configurations are available to meet specific logistical requirements. Proper storage in a cool, ventilated environment is recommended to maintain product integrity over time. Our commitment to safety and regulatory compliance ensures that all materials are handled according to international chemical safety standards.

For bulk inquiries or technical documentation regarding 3-Fluoro-2-methylbenzaldehyde, our support team is ready to assist global partners. We prioritize reliable supply chains and timely delivery to support your research and production schedules without interruption.