Intermediates

3-Fluoro-2-methylbenzoic acid

  • CAS No.699-90-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Fluoro-2-methylbenzoic acid (CAS 699-90-1) designed for advanced organic synthesis and pharmaceutical building block applications.

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Product Technical Details

Product Overview

3-Fluoro-2-methylbenzoic acid represents a critical fluorinated building block within the realm of advanced organic synthesis and medicinal chemistry. As a substituted aromatic carboxylic acid, this compound integrates the unique electronic properties of the fluorine atom with the steric influence of an ortho-methyl group. These structural features make it an invaluable precursor for the development of complex pharmaceutical agents, agrochemical formulations, and functional materials. Our manufacturing process ensures high consistency and reliability, catering to the rigorous demands of both research laboratories and large-scale production environments.

The strategic introduction of fluorine into organic molecules is known to enhance metabolic stability, lipophilicity, and bioavailability, which is why this intermediate is frequently sought after in modern drug discovery campaigns. We provide this material with strict quality controls to support seamless downstream reactions, ensuring that your synthesis pathways proceed with maximum efficiency and yield.

Key Specifications

Quality is paramount in chemical manufacturing, and our commitment to excellence is reflected in the comprehensive analytical testing performed on every batch. Our 3-Fluoro-2-methylbenzoic acid undergoes verification for identity, purity, and physical properties. The following table outlines the standard physical and chemical properties associated with this product, ensuring transparency for our global partners.

ParameterSpecification
Chemical Name3-Fluoro-2-methylbenzoic acid
CAS Number699-90-1
Molecular FormulaC8H7FO2
Molecular Weight154.14 g/mol
AppearanceOff-white to white powder
Purity (HPLC)≥99.0%
Melting Point158-160°C
Density1.258 g/cm3
Boiling Point261.2°C

Each certificate of analysis (COA) is generated per batch, ensuring full traceability and compliance with international quality standards. We utilize high-performance liquid chromatography to guarantee the purity levels meet or exceed the specified thresholds.

Industrial Applications

This fluorinated benzoic acid derivative serves as a versatile intermediate across multiple chemical sectors. In the pharmaceutical industry, it is utilized in the synthesis of kinase inhibitors and other therapeutic candidates where fluorine substitution is required to modulate pharmacokinetic properties. The ortho-methyl group provides specific steric hindrance that can influence reaction selectivity during coupling processes, offering chemists greater control over synthetic outcomes.

  • Pharmaceutical Intermediate: Used in multi-step synthesis routes for novel drug candidates and active pharmaceutical ingredients.
  • Agrochemical Production: Acts as a key building block for herbicides and pesticides requiring fluorinated aromatic structures for enhanced efficacy.
  • Material Science: Employed in the creation of polymers and liquid crystals with enhanced thermal stability and performance characteristics.
  • Organic Synthesis: Suitable for amidation, esterification, and cross-coupling reactions such as Suzuki or Buchwald-Hartwig protocols.

Our technical team can provide guidance on optimal storage and handling to maintain chemical integrity during your synthesis workflow, ensuring safety and performance.

Quality Assurance and Packaging

We adhere to strict quality management systems to guarantee product safety and performance across all shipments. All materials are stored in cool, ventilated facilities to prevent degradation from moisture or heat exposure. Standard packaging includes 25 kg drums, which are designed to protect the contents from physical damage and environmental factors during international transit. Custom packaging solutions are available upon request to suit specific logistical requirements or smaller scale research needs.

Global shipping capabilities ensure timely delivery to laboratories and production sites worldwide. We invite partners to request samples for evaluation and discuss bulk pricing options tailored to project scales. Our commitment to excellence makes us a preferred supplier for high-purity chemical intermediates, supporting innovation in chemistry and manufacturing.