Intermediates

3-Fluoro-2-methylphenol

  • CAS No.443-87-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Fluoro-2-methylphenol (CAS 443-87-8) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

3-Fluoro-2-methylphenol is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by the strategic placement of a fluorine atom adjacent to a methyl group on the phenolic ring, this molecule offers unique electronic and steric properties that are highly valued in medicinal chemistry and fine chemical manufacturing. Our facility produces this intermediate under strict quality control standards to ensure consistency across batches, making it an ideal choice for research and industrial scale applications.

The introduction of fluorine into organic molecules often enhances metabolic stability and bioavailability, which is why this compound is frequently utilized in the development of novel pharmaceutical agents. As a trusted global manufacturer, we understand the precise requirements needed for downstream synthesis and provide material that meets rigorous purity specifications.

Key Specifications

ParameterValue
CAS Number443-87-8
Molecular FormulaC7H7FO
Molecular Weight126.128
AppearanceColorless to light yellow liquid
Assay≥98.0%
Density1.2±0.1 g/cm3
Boiling Point187.9±20.0 °C at 760 mmHg
Melting Point53.2-53.9ºC
Flash Point78.5±10.5 °C
Refractive Index1.520

Industrial Applications

This fluorinated phenol derivative is primarily employed as an intermediate in the synthesis of complex organic molecules. Its reactivity profile allows for various substitution reactions, making it versatile for creating diverse chemical architectures. Key application areas include the production of active pharmaceutical ingredients (APIs), where fluorine substitution is often key to optimizing drug performance. Additionally, it finds use in agrochemical formulations and the development of advanced materials requiring specific thermal or chemical resistance.

Researchers utilize this compound for structure-activity relationship (SAR) studies, leveraging its specific substitution pattern to explore new therapeutic pathways. The high purity level ensures that side reactions are minimized during subsequent synthetic steps, improving overall yield and efficiency in production processes.

Quality Assurance and Safety

We adhere to international quality management systems to guarantee that every drum of 3-Fluoro-2-methylphenol meets the stated specifications. Each batch is accompanied by a Certificate of Analysis (COA) detailing test results for identity, purity, and physical constants. Our logistics team ensures secure packaging, typically 200 kg per drum, though custom packaging solutions are available to meet specific client requirements.

Regarding safety, this material should be stored in a cool, ventilated place away from incompatible substances. Proper personal protective equipment (PPE) is recommended during handling to prevent exposure. We provide comprehensive technical support and safety data sheets (SDS) to ensure safe integration into your manufacturing workflow. Partner with us for reliable supply chains and competitive bulk pricing on this essential chemical intermediate.