Intermediates

3-Fluoro-2-methylpyridine

  • CAS No.15931-15-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Fluoro-2-methylpyridine (CAS 15931-15-4) designed for advanced pharmaceutical synthesis and organic chemistry applications.

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Product Technical Details

Product Overview

3-Fluoro-2-methylpyridine is a specialized fluorinated heterocyclic compound that serves as a critical building block in modern medicinal chemistry and agrochemical development. As a key pharmaceutical intermediate, this compound enables the introduction of fluorine atoms into complex molecular structures, enhancing metabolic stability and bioavailability in final drug candidates. Our manufacturing process ensures exceptional consistency and purity, making it an ideal choice for research laboratories and large-scale production facilities alike.

The strategic placement of the fluorine atom at the third position of the pyridine ring offers unique reactivity profiles, allowing chemists to perform selective substitutions and coupling reactions with high precision. This versatility makes 3-Fluoro-2-methylpyridine indispensable in the synthesis of kinase inhibitors, receptor modulators, and other therapeutic agents targeting various disease states.

Technical Specifications

We adhere to strict quality control protocols to guarantee that every batch meets or exceeds industry standards. The following table outlines the key physical and chemical properties of our premium grade product:

ParameterSpecification
Chemical Name3-Fluoro-2-methylpyridine
CAS Number15931-15-4
Molecular FormulaC6H6FN
Molecular Weight111.12 g/mol
AppearanceColorless liquid
Purity≥99.0%
Density1.077 g/cm3
Boiling Point113.9°C at 760 mmHg
Flash Point22.7°C
Refractive Index1.477

Industrial Applications

This fluorinated pyridine derivative is primarily utilized in the pharmaceutical industry for the construction of complex active pharmaceutical ingredients (APIs). Its role as a synthon allows for the efficient development of novel therapeutics with improved pharmacokinetic profiles. Beyond human medicine, it finds applications in the agrochemical sector for creating advanced crop protection agents that require specific electronic properties provided by the fluorine substituent.

Researchers value this compound for its stability under various reaction conditions, facilitating multi-step synthesis routes without significant degradation. Whether used in cross-coupling reactions, nucleophilic substitutions, or as a ligand in catalytic processes, 3-Fluoro-2-methylpyridine delivers reliable performance.

Quality Assurance and Safety

Our facility operates under rigorous quality management systems to ensure product integrity. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results for purity, identity, and physical constants. We employ advanced analytical techniques such as GC-MS and NMR spectroscopy to verify composition.

Regarding safety, this chemical should be handled in a well-ventilated environment using appropriate personal protective equipment. It is classified as a flammable liquid, requiring storage away from ignition sources. Our packaging ensures secure transport while maintaining chemical stability during transit.

Storage and Logistics

To maintain optimal quality, store 3-Fluoro-2-methylpyridine in a tightly closed container within a cool, dry, and well-ventilated area. Avoid exposure to direct sunlight and moisture. We offer flexible packaging options, including standard 25kg drums, to accommodate varying production scales. Our global logistics network ensures timely delivery to customers worldwide, supported by detailed documentation for customs clearance.