Intermediates

3-Fluoro-4-aminobenzonitrile

  • CAS No.63069-50-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Fluoro-4-aminobenzonitrile designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

3-Fluoro-4-aminobenzonitrile is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by the presence of both an amino group and a nitrile moiety on a fluorinated benzene ring, this chemical offers unique reactivity profiles essential for constructing complex molecular architectures. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream pharmaceutical and agrochemical manufacturing processes.

The introduction of fluorine into organic molecules often enhances metabolic stability and bioavailability, making this compound particularly valuable in medicinal chemistry research. Whether utilized in the development of novel therapeutic agents or advanced material science applications, 3-Fluoro-4-aminobenzonitrile provides a robust foundation for chemical innovation. We are committed to supplying global partners with materials that meet rigorous international standards.

Key Specifications

Quality assurance is paramount in the production of fine chemical intermediates. Our manufacturing process employs advanced purification techniques to achieve high purity levels suitable for sensitive synthetic routes. The physical properties are tightly monitored to ensure batch-to-batch consistency, facilitating smooth integration into your production lines.

ParameterSpecification
Chemical Name3-Fluoro-4-aminobenzonitrile
CAS Number63069-50-1
Molecular FormulaC7H5FN2
Molecular Weight136.126 g/mol
AppearanceOff-white powder
Assay≥98.0%
Melting Point70-74 °C
Boiling Point264.2±25.0 °C at 760 mmHg
Density1.3±0.1 g/cm3

Industrial Applications

This fluorinated nitrile derivative is predominantly utilized as a key intermediate in the synthesis of pharmaceutical active ingredients. The nitrile group serves as a versatile handle for further functionalization, allowing chemists to convert it into amines, acids, or heterocycles depending on the target molecule requirements. Additionally, the fluorine atom acts as a bioisostere, often improving the pharmacokinetic properties of the final drug candidate.

  • Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and other targeted therapies.
  • Agrochemical Synthesis: Serves as a precursor for developing novel pesticides and herbicides.
  • Material Science: Applied in the creation of specialized polymers and organic electronic materials.
  • Research and Development: Essential for library synthesis in drug discovery programs.

Storage and Handling

To maintain the integrity and stability of 3-Fluoro-4-aminobenzonitrile, proper storage conditions are essential. The product should be kept in a cool, ventilated area away from direct sunlight and moisture sources. Containers must remain tightly sealed when not in use to prevent contamination or degradation. We recommend following standard laboratory safety procedures when handling this chemical, including the use of appropriate personal protective equipment.

Our packaging options are designed to ensure safe transit across global supply chains. Standard packing includes 25 kg drums, but we also accommodate custom packaging requirements based on specific customer needs. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with stated specifications. For bulk orders or technical inquiries regarding synthesis routes, our expert team is available to provide comprehensive support.