3-Fluoro-4-methoxyacetophenone
- CAS No.455-91-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 3-Fluoro-4-methoxyacetophenone (CAS 455-91-4) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical manufacturing.
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Product Overview
3-Fluoro-4-methoxyacetophenone is a specialized fluorinated aromatic ketone that serves as a critical building block in modern organic synthesis. This compound features a unique substitution pattern with both fluoro and methoxy groups on the phenyl ring, providing distinct electronic and steric properties that are highly valued in medicinal chemistry and material science. As a key intermediate, it facilitates the construction of complex molecular architectures required for high-performance pharmaceuticals and agrochemicals.
Our manufacturing process ensures exceptional consistency and purity levels, meeting the rigorous demands of industrial research and production scales. The presence of the fluorine atom enhances metabolic stability and bioavailability in downstream drug candidates, while the methoxy group offers versatile handles for further functionalization. We prioritize safety and quality throughout the supply chain, delivering a product that supports efficient synthetic routes.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 3-Fluoro-4-methoxyacetophenone |
| CAS Number | 455-91-4 |
| Molecular Formula | C9H9FO2 |
| Molecular Weight | 168.17 g/mol |
| Appearance | Yellowish solid |
| Assay | ≥99.0% |
| Melting Point | 92-94°C |
| Boiling Point | 147-148°C |
| Moisture Content | ≤0.2% |
Industrial Applications
This fluorinated ketone is extensively utilized across multiple high-value sectors. In the pharmaceutical industry, it acts as a precursor for kinase inhibitors and other therapeutic agents targeting neurological and oncological conditions. The specific positioning of substituents allows for selective reactions, reducing byproduct formation and improving overall yield in multi-step syntheses.
- Pharmaceutical Intermediate: Essential for synthesizing active pharmaceutical ingredients (APIs) with enhanced pharmacokinetic profiles.
- Agrochemical Synthesis: Used in the development of novel pesticides and herbicides requiring robust chemical stability.
- Material Science: Applied in the creation of specialized polymers and liquid crystals where fluorine content modifies physical properties.
- Research and Development: A standard reagent for academic and industrial laboratories exploring new organic transformations.
Quality Assurance and Storage
We maintain a comprehensive quality management system to guarantee product integrity. Every batch undergoes strict analytical testing, including HPLC and NMR verification, to confirm identity and purity. A Certificate of Analysis (COA) is provided with each shipment, ensuring full transparency and compliance with international standards. Our facility adheres to good manufacturing practices to minimize contamination risks.
For optimal preservation, store this compound in a cool, ventilated area away from direct sunlight and moisture. The standard packaging consists of 25 kg drums, which are designed to protect the material during transit. Custom packaging solutions are available upon request to accommodate specific logistical requirements. We support global shipping with reliable documentation to facilitate smooth customs clearance for international partners.
