3-Fluoro-4-methoxybenzoic acid
- CAS No.403-20-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Fluoro-4-methoxybenzoic acid (CAS 403-20-3), a versatile fluorinated aromatic intermediate for advanced organic synthesis.
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Product Overview
3-Fluoro-4-methoxybenzoic acid is a high-value fluorinated aromatic carboxylic acid widely employed as a key building block in the pharmaceutical and agrochemical industries. With its unique combination of electron-withdrawing fluorine and electron-donating methoxy substituents on the benzoic acid scaffold, this compound offers exceptional reactivity and selectivity in cross-coupling reactions, heterocycle formation, and functional group interconversions. Our product is manufactured under stringent quality control protocols to ensure consistent performance in complex synthetic pathways.
Specifications
| Molecular Formula | C8H7FO3 |
|---|---|
| Molecular Weight | 170.14 g/mol |
| CAS Number | 403-20-3 |
| Appearance | Off-white powder |
| Assay | ≥98.0% |
| Moisture | ≤0.5% |
| Melting Point | 211–213°C |
| Density | 1.568 g/cm³ |
| Boiling Point | 352.5°C |
| Flash Point | 167°C |
Industrial Applications
As a specialty fluoroaromatic intermediate, 3-Fluoro-4-methoxybenzoic acid serves critical roles in multi-step syntheses requiring precise electronic and steric tuning. Its primary applications include:
- Pharmaceutical R&D: Precursor for novel active pharmaceutical ingredients (APIs) targeting metabolic and neurological pathways.
- Agrochemical Innovation: Building block for next-generation herbicides and fungicides with enhanced environmental profiles.
- Material Science: Intermediate in the production of liquid crystals and specialty polymers.
- Chemical Research: Valuable substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed transformations.
Stored in a cool, dry, and well-ventilated area, this compound maintains stability under recommended conditions. Standard packaging is 25 kg per drum, with custom options available to meet specific logistical or regulatory requirements.
