Intermediates

3-Fluoro-4-methoxybenzonitrile

  • CAS No.331-62-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Fluoro-4-methoxybenzonitrile (CAS 331-62-4) serves as a critical fluorinated building block for advanced organic synthesis and pharmaceutical intermediate production.

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Product Technical Details

Product Overview

3-Fluoro-4-methoxybenzonitrile is a specialized fluorinated aromatic compound widely recognized for its utility in modern organic synthesis. As a key building block, this chemical facilitates the construction of complex molecular architectures required in pharmaceutical research and agrochemical development. Our manufacturing process ensures consistent quality and high purity levels, making it a reliable choice for industrial scale applications. The presence of both fluoro and methoxy substituents on the benzene ring provides unique reactivity profiles, enabling diverse synthetic transformations.

Technical Specifications

ParameterValue
CAS Number331-62-4
Molecular FormulaC8H6FNO
Molecular Weight151.138 g/mol
AppearanceOff-white powder
Assay≥98.0%
Melting Point98-100°C
Boiling Point254.3±20.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point107.6±21.8 °C
Refractive Index1.505

Industrial Applications

This compound functions primarily as an intermediate in the synthesis of higher-value active pharmaceutical ingredients. The fluorine atom enhances metabolic stability and bioavailability in drug candidates, while the nitrile group offers a versatile handle for further functionalization such as hydrolysis to carboxylic acids or reduction to amines. Researchers utilize this material in cross-coupling reactions and nucleophilic aromatic substitutions. It is particularly valuable in the development of kinase inhibitors and other targeted therapies where specific substitution patterns are required.

Quality And Storage

We adhere to strict quality control protocols to guarantee product integrity. Each batch is accompanied by a Certificate of Analysis verifying purity and physical constants. For optimal stability, store this material in a cool, ventilated area away from direct sunlight and moisture. Packaging is available in 25 kg drums, with custom options available upon request to suit specific logistical needs. Our global supply chain ensures timely delivery for large-scale manufacturing projects.