3-Fluoro-5-bromophenol
- CAS No.433939-27-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Fluoro-5-bromophenol (CAS 433939-27-6) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical intermediates.
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Product Overview
3-Fluoro-5-bromophenol stands as a pivotal halogenated aromatic compound within the landscape of modern fine chemical synthesis. As a specialized fluorinated intermediate, this substance offers unique reactivity profiles that are essential for constructing complex molecular architectures. Our manufacturing process ensures that every batch meets rigorous international standards, providing researchers and industrial partners with a reliable foundation for their synthetic pathways. The strategic placement of both fluorine and bromine substituents on the phenolic ring enables versatile functionalization, making it a preferred choice for medicinal chemistry and material science applications.
We understand the critical nature of supply chain consistency in the pharmaceutical and agrochemical sectors. Therefore, our production facilities are equipped with advanced purification technologies to guarantee high chemical purity and minimal impurity profiles. This commitment to quality allows downstream manufacturers to optimize their reaction yields and reduce waste during subsequent synthetic steps.
Technical Specifications
Quality control is paramount in the production of sensitive chemical intermediates. Each lot undergoes comprehensive analytical testing to verify identity and purity. The following table outlines the key physical and chemical properties associated with this product:
| Parameter | Specification |
|---|---|
| CAS Number | 433939-27-6 |
| Molecular Formula | C6H4BrFO |
| Molecular Weight | 190.998 g/mol |
| Appearance | Off-white crystalline powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 42ºC |
| Boiling Point | 231.1±20.0 ºC at 760 mmHg |
| Density | 1.8±0.1 g/cm3 |
| Flash Point | 93.6±21.8 ºC |
| Refractive Index | 1.576 |
Industrial Applications
The versatility of 3-Fluoro-5-bromophenol makes it indispensable in various high-value industries. Its primary utility lies in serving as a building block for the synthesis of more complex organic molecules. The presence of the bromine atom facilitates cross-coupling reactions, such as Suzuki, Heck, or Sonogashira couplings, while the hydroxyl group offers sites for etherification or esterification. The fluorine atom contributes to metabolic stability and lipophilicity in final drug candidates.
- Pharmaceutical Intermediate Synthesis: Used in the development of novel therapeutic agents requiring specific substitution patterns.
- Agrochemical Formulations: Acts as a precursor for herbicides and pesticides with enhanced environmental profiles.
- Material Science: Employed in the creation of specialized polymers and liquid crystal materials.
- Research and Development: Supports academic and industrial labs in structure-activity relationship (SAR) studies.
Quality Assurance and Logistics
We adhere to strict quality management systems to ensure product integrity from synthesis to delivery. Every shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. Our packaging options are designed to maintain stability during transit, typically utilizing 25 kg drums or customized containers based on client requirements. Proper storage in a cool, ventilated area away from incompatible substances is recommended to preserve shelf life. As a global manufacturer, we offer competitive bulk pricing and reliable logistics support to meet the dynamic demands of the international chemical market.
