Intermediates

3-Fluoro-5-methylbenzoic acid

  • CAS No.518070-19-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Fluoro-5-methylbenzoic acid (CAS 518070-19-4) designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

3-Fluoro-5-methylbenzoic acid is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. As a key intermediate, this chemical facilitates the construction of complex molecular architectures required in pharmaceutical development, agrochemical formulations, and advanced material science. The introduction of a fluorine atom at the meta position enhances the metabolic stability and lipophilicity of downstream products, making this compound highly valuable for medicinal chemistry programs focused on novel therapeutic agents.

Our manufacturing facility adheres to strict quality management systems to ensure every batch meets rigorous international standards. We understand that consistency in chemical properties is paramount for reproducible synthesis outcomes. Therefore, each production lot undergoes comprehensive analytical testing to verify identity, purity, and physical characteristics before release.

Technical Specifications

The following table outlines the key physical and chemical properties of our premium grade 3-Fluoro-5-methylbenzoic acid. These parameters are essential for process chemists when designing reaction conditions and scaling up production.

ParameterValue
CAS Number518070-19-4
Molecular FormulaC8H7FO2
Molecular Weight154.14 g/mol
AppearanceWhite powder
Purity (HPLC)≥99.0%
Melting Point103°C
Boiling Point332.7°C
Density1.373 g/cm³
Flash Point155°C
Refractive Index1.582

Industrial Applications

This fluorinated benzoic acid derivative is primarily utilized as a versatile intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its structural features allow for various functional group transformations, including amidation, esterification, and cross-coupling reactions. Beyond pharmaceuticals, it finds application in the development of high-performance polymers and liquid crystal materials where thermal stability and specific electronic properties are required.

  • Pharmaceutical intermediate for kinase inhibitors and receptor modulators.
  • Building block for agrochemical herbicides and fungicides.
  • Component in specialty polymer synthesis.
  • Reagent for medicinal chemistry library construction.

Quality Assurance and Packaging

We prioritize product integrity throughout the supply chain. The material is packaged in secure 25 kg drums lined with moisture-resistant materials to prevent degradation during transit. Custom packaging solutions are available upon request to accommodate specific logistical requirements or smaller scale research needs. Every shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results.

Storage and Handling

To maintain optimal quality, 3-Fluoro-5-methylbenzoic acid should be stored in a cool, ventilated area away from direct sunlight and incompatible substances. Containers must be kept tightly closed when not in use to prevent moisture absorption. Proper personal protective equipment (PPE) should be worn during handling to ensure safety in accordance with standard laboratory and industrial hygiene protocols. Our technical support team is available to provide detailed safety data sheets and handling guidance for large-scale integration.