3-Fluoro-5-nitrotoluene
- CAS No.499-08-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 3-Fluoro-5-nitrotoluene (CAS 499-08-1) for organic synthesis. Reliable supply with ≥98.0% assay, suitable for pharmaceutical and agrochemical intermediate production.
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Product Overview
3-Fluoro-5-nitrotoluene is a specialized fluorinated aromatic compound widely utilized in advanced organic synthesis and chemical manufacturing. As a key intermediate, it serves as a crucial building block for the development of pharmaceuticals, agrochemicals, and functional materials. Our manufacturing process ensures high purity levels, meeting the rigorous demands of modern chemical research and industrial production. The compound features a stable nitro group and a reactive fluorine atom, enabling diverse substitution reactions essential for complex molecule construction.
In the realm of fine chemicals, this substance stands out due to its unique reactivity profile. The presence of the fluorine atom at the meta position relative to the methyl group enhances the electrophilic character of the aromatic ring, facilitating nucleophilic aromatic substitution. This makes it an ideal precursor for synthesizing complex heterocyclic structures found in next-generation therapeutic agents. Furthermore, the nitro group can be reduced to an amine, opening pathways to aniline derivatives essential for dye and polymer industries.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 3-Fluoro-5-nitrotoluene |
| CAS Number | 499-08-1 |
| Molecular Formula | C7H6FNO2 |
| Molecular Weight | 155.126 |
| Appearance | Yellow crystalline powder |
| Assay | ≥98.0% |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 230.0±20.0 °C at 760 mmHg |
| Flash Point | 92.9±21.8 °C |
| Refractive Index | 1.530 |
Industrial Applications
This chemical intermediate is primarily employed in the synthesis of various organic compounds. Its specific substitution pattern allows chemists to introduce fluorine into molecular scaffolds, which is a common strategy to improve metabolic stability and bioavailability in drug design. Additionally, it is used in the production of agrochemicals where fluorinated structures enhance pesticidal activity. The versatility of this compound supports applications in material science, particularly in the creation of liquid crystals and high-performance polymers.
- Pharmaceutical intermediate synthesis
- Agrochemical formulation development
- Fluorinated polymer production
- Liquid crystal material manufacturing
- Research and development reagent
Quality Assurance and Storage
Our facility adheres to strict quality management systems to ensure product consistency. Every batch undergoes comprehensive testing using high-performance liquid chromatography and gas chromatography-mass spectrometry to verify assay purity and impurity profiles. We provide full documentation including Certificates of Analysis and Material Safety Data Sheets. Packaging is designed to maintain stability during transit, utilizing durable drums that protect against moisture and light exposure.
Safety handling is paramount for all chemical operations. Personnel should utilize appropriate personal protective equipment including gloves and safety goggles. Storage requires a cool, ventilated environment away from incompatible substances such as strong oxidizers. By choosing our product, clients gain access to a reliable supply chain backed by decades of expertise in fluorinated chemistry. We offer flexible packaging options including standard 25 kg drums or custom solutions based on specific client requirements.
