Intermediates

3-Fluoro-5-(trifluoromethyl)benzonitrile

  • CAS No.149793-69-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Fluoro-5-(trifluoromethyl)benzonitrile (CAS 149793-69-1) designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

3-Fluoro-5-(trifluoromethyl)benzonitrile is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Identified by CAS number 149793-69-1, this chemical features a unique structural arrangement combining a nitrile group with both fluoro and trifluoromethyl substituents on the benzene ring. This specific substitution pattern imparts distinct electronic and steric properties, making it an invaluable precursor for the development of complex pharmaceutical agents and agrochemical formulations.

Our manufacturing process ensures exceptional consistency and quality, catering to the rigorous demands of research laboratories and industrial production facilities. The presence of fluorine atoms enhances metabolic stability and lipophilicity in downstream molecules, which is a key consideration in medicinal chemistry design. As a trusted global manufacturer, we prioritize safety and compliance throughout the production lifecycle.

Technical Specifications

We adhere to strict quality control protocols to guarantee the integrity of every batch. The following table outlines the key physical and chemical properties verified during our comprehensive testing phase.

ParameterValue
CAS Number149793-69-1
Molecular FormulaC8H3F4N
Molecular Weight189.110 g/mol
AppearanceLight yellow liquid
Assay (Purity)≥98.0%
Density1.4±0.1 g/cm3
Boiling Point179.9±35.0 °C at 760 mmHg
Flash Point65.6±0.0 °C
Refractive Index1.444

Industrial Applications

This fluorinated nitrile derivative is primarily utilized as an intermediate in the synthesis of high-value organic compounds. Its versatility allows for various chemical transformations, including hydrolysis to carboxylic acids or reduction to amines, facilitating the construction of diverse molecular architectures.

  • Pharmaceutical Intermediates: Used in the development of kinase inhibitors and other therapeutic candidates where fluorine substitution improves bioavailability.
  • Agrochemical Synthesis: Serves as a precursor for novel pesticides and herbicides requiring enhanced environmental stability.
  • Material Science: Applied in the creation of specialized polymers and liquid crystals with unique electronic properties.
  • Research and Development: Essential for medicinal chemistry programs focused on structure-activity relationship studies.

Quality Assurance and Handling

Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified parameters. We recommend storing this product in a cool, ventilated area away from direct sunlight and incompatible materials. Proper handling procedures should be followed to maintain stability and safety. Packaging is available in 200 kg drums or customized according to specific client requirements to facilitate global logistics.

For detailed technical data sheets or inquiries regarding bulk pricing and manufacturing capabilities, please contact our sales team. We are committed to supporting your synthesis projects with reliable supply chains and premium-grade chemical solutions.