3-Fluoro-6-Methylpyridin-2-Amine
- CAS No.1211520-83-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used in organic synthesis. Ideal for medicinal chemistry research and large-scale production.
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Product Overview
3-Fluoro-6-Methylpyridin-2-Amine represents a high-value fluorinated heterocyclic building block essential for modern pharmaceutical innovation. This specialized amine derivative is engineered to support the complex requirements of medicinal chemistry and organic synthesis. The strategic placement of the fluorine atom on the pyridine ring significantly influences the electronic properties of the molecule, offering chemists unique opportunities to modulate reactivity and binding affinity in downstream drug candidates. As the pharmaceutical industry increasingly relies on fluorinated scaffolds to improve metabolic stability and membrane permeability, this intermediate has become a crucial component in the development of next-generation therapeutics.
Our production facility utilizes advanced synthetic routes to ensure high yield and exceptional purity levels. We recognize that consistency is paramount in drug development, which is why every batch is manufactured under strict quality management systems. Whether you are conducting early-stage lead optimization or scaling up for clinical trial material production, our 3-Fluoro-6-Methylpyridin-2-Amine provides the reliability needed to maintain project timelines and scientific integrity.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Fluoro-6-Methylpyridin-2-Amine |
| CAS Registry Number | 1211520-83-0 |
| Molecular Formula | C6H7FN2 |
| Molecular Weight | 126.13 g/mol |
| Purity Grade | ≥99.0% (HPLC) |
| Physical Appearance | Off-white to Light Yellow Crystalline Solid |
| Storage Conditions | Cool, Dry, Sealed Container |
Applications in Pharmaceutical Science
The primary application of this compound lies in its role as a versatile intermediate for Active Pharmaceutical Ingredient (API) synthesis. The pyridine core is a privileged structure in drug design, found in numerous approved medications across various therapeutic areas. By incorporating the fluoro and methyl substituents, chemists can fine-tune the pharmacokinetic profile of the final drug product. This molecule is particularly useful in the construction of kinase inhibitors, anti-inflammatory agents, and central nervous system therapeutics where specific electronic and steric properties are required.
- Core Scaffold for Heterocyclic Drug Synthesis
- Building Block for Combinatorial Chemistry Libraries
- Intermediate for Agrochemical Development
- Reagent for Cross-Coupling Reactions
- Material for Structure-Activity Relationship (SAR) Studies
Quality Control and Compliance
Quality assurance is the cornerstone of our manufacturing operation. Each production lot of 3-Fluoro-6-Methylpyridin-2-Amine undergoes comprehensive analytical validation. We employ state-of-the-art instrumentation including High-Performance Liquid Chromatography (HPLC), Nuclear Magnetic Resonance (NMR), and Mass Spectrometry (MS) to verify chemical identity and assess impurity profiles. A detailed Certificate of Analysis (COA) is generated for every shipment, providing full transparency regarding product quality. This documentation is essential for regulatory filings and quality audits within the pharmaceutical supply chain.
Storage and Handling Guidelines
To maintain the integrity of this chemical intermediate, proper storage protocols must be followed. The material should be kept in a tightly sealed container to prevent exposure to atmospheric moisture and oxygen, which could potentially degrade quality over time. Ideal storage environments are cool and dry, with temperatures maintained within standard laboratory ranges. Avoid direct exposure to strong light or heat sources. When handling, standard laboratory safety precautions should be observed, including the use of appropriate personal protective equipment (PPE) such as gloves and safety goggles. For detailed safety information, please refer to the Material Safety Data Sheet (MSDS) provided with your order.
We are committed to delivering excellence in every package. Our logistics team ensures secure packaging and timely global delivery to support your research and production needs. For inquiries regarding bulk quantities, custom synthesis capabilities, or technical support, please contact our sales representatives. We look forward to partnering with you to advance your chemical projects.
