Intermediates

3-Fluoroanisole

  • CAS No.456-49-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

3-Fluoroanisole is a high-purity liquid intermediate essential for pharmaceutical synthesis. We offer bulk quantities with strict quality control and global delivery.

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Product Technical Details

Product Overview

3-Fluoroanisole, also known as M-Fluoroanisole, is a critical organic compound widely utilized in the field of advanced chemical synthesis. As a fluorinated aromatic ether, it serves as a fundamental building block for the development of complex pharmaceutical agents and agrochemical products. Our facility specializes in the production of this high-quality intermediate, ensuring consistent molecular integrity and performance across various industrial applications.

The introduction of a fluorine atom into the anisole structure significantly alters the electronic properties of the molecule, enhancing metabolic stability and lipophilicity in downstream drug candidates. This makes 3-Fluoroanisole an invaluable reagent for medicinal chemists aiming to optimize lead compounds. We maintain rigorous production standards to deliver a product that meets the demanding requirements of modern organic synthesis laboratories and large-scale manufacturing plants.

Physical And Chemical Properties

Understanding the physicochemical characteristics of 3-Fluoroanisole is essential for safe handling and effective integration into synthesis routes. The compound presents as a light yellow liquid at standard temperature and pressure, with a distinct aromatic odor typical of substituted benzene derivatives. Its relatively high boiling point allows for stable processing under various reaction conditions, while its density ensures predictable behavior in separation processes.

The presence of the methoxy group alongside the fluorine substituent creates a unique reactivity profile, facilitating selective nucleophilic substitutions and cross-coupling reactions. Our quality control team verifies every batch against standard reference materials to confirm parameters such as refractive index and flash point, ensuring safety and reliability during storage and transportation.

Technical Specifications

We adhere to strict internal quality management systems to guarantee that every drum of 3-Fluoroanisole meets or exceeds industry standards. The following table outlines the key specification parameters for our standard commercial grade product. Custom specifications may be available upon request for specific research or production needs.

ParameterSpecification
CAS Number456-49-5
Molecular FormulaC7H7FO
Molecular Weight126.13 g/mol
AppearanceLight yellow liquid
Purity≥99.0%
Density1.104 g/mL at 25 °C
Boiling Point158 °C at 743 mm Hg
Flash Point111 °F
Refractive Index1.488

Industrial Applications

The primary application of 3-Fluoroanisole lies in the synthesis of pharmaceutical intermediates. It is frequently employed in the preparation of biologically active molecules where fluorine substitution is required to improve bioavailability or binding affinity. Additionally, this compound serves as a versatile precursor in the manufacture of specialty chemicals, including liquid crystals and advanced polymers.

Research institutions utilize this material for developing new catalytic processes and exploring structure-activity relationships in drug discovery programs. Our global clientele relies on our consistent supply chain to maintain their production schedules without interruption. Whether used in small-scale laboratory experiments or multi-ton industrial campaigns, our product delivers reliable performance.

Storage And Handling

Proper storage is crucial to maintain the quality and safety of 3-Fluoroanisole. The product should be kept in a tightly closed container to prevent contamination and moisture absorption. It is recommended to store the material in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents.

Personnel handling this chemical should wear appropriate personal protective equipment, including chemical-resistant gloves and safety goggles. In case of spillage, standard hazardous material containment procedures should be followed immediately. We provide comprehensive safety data sheets with every shipment to ensure compliance with local regulations and workplace safety standards.

Quality Assurance And Support

As a dedicated global manufacturer, we understand the importance of documentation and traceability. Each batch of 3-Fluoroanisole is accompanied by a Certificate of Analysis (COA) detailing the test results for purity and physical constants. Our technical support team is available to assist with application queries, ensuring that our customers achieve optimal results in their synthesis processes.