3-Fluorophenyl Isothiocyanate
- CAS No.404-72-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Fluorophenyl Isothiocyanate (CAS 404-72-8) designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
3-Fluorophenyl Isothiocyanate is a highly versatile organic compound widely recognized for its significant role in modern chemical synthesis. Characterized by the presence of a fluorine atom at the meta position on the phenyl ring coupled with a reactive isothiocyanate functional group, this substance serves as a critical building block in the development of complex molecular structures. The electronegative fluorine substituent enhances the metabolic stability and bioavailability of downstream products, making it particularly valuable in medicinal chemistry and agrochemical research.
Our manufacturing process ensures exceptional consistency and reliability. Produced under strict quality control protocols, this chemical meets the rigorous demands of industrial-scale synthesis and laboratory research. The isothiocyanate moiety offers high reactivity towards nucleophiles, especially amines, facilitating the efficient formation of thiourea derivatives which are foundational structures in numerous pharmaceutical APIs and functional materials.
Technical Specifications
We adhere to international standards to guarantee the purity and performance of every batch. The following table outlines the key physical and chemical properties verified through our analytical laboratories.
| Parameter | Specification |
|---|---|
| CAS Number | 404-72-8 |
| Molecular Formula | C7H4FNS |
| Molecular Weight | 153.177 g/mol |
| Appearance | Almost colorless transparent liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 227.8±13.0 °C at 760 mmHg |
| Flash Point | 85.0±0.0 °C |
Industrial Applications
This compound is primarily utilized as a key intermediate in the synthesis of diverse organic molecules. Its applications span across several high-value sectors including pharmaceuticals, agrochemicals, and material sciences. In drug discovery, it is frequently employed to introduce fluorinated phenylthiourea motifs into lead compounds, aiding in structure-activity relationship studies. Additionally, it serves as a precursor for producing specialized polymers and corrosion inhibitors.
The versatility of 3-Fluorophenyl Isothiocyanate allows chemists to explore novel reaction pathways. Its compatibility with various synthetic routes makes it an indispensable reagent for creating heterocyclic compounds and conjugated systems. Researchers value this material for its predictable reactivity profile and high yield potential in coupling reactions.
Quality Assurance and Handling
Safety and quality are paramount in our operations. Each production batch undergoes comprehensive testing using advanced chromatography and spectroscopy methods to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your internal quality standards.
- Store in a cool, ventilated place away from direct sunlight.
- Keep containers tightly closed when not in use to prevent moisture absorption.
- Handle with appropriate personal protective equipment including gloves and eye protection.
- Avoid contact with strong oxidizing agents and amines during storage.
We offer flexible packaging solutions to meet specific logistical requirements, ranging from standard drums to customized containers. Our global supply chain ensures timely delivery while maintaining product integrity throughout transit. For technical inquiries or bulk procurement requests, our expert team is ready to provide detailed support and competitive pricing structures tailored to your project needs.
