3-Fluoropicolinic Acid
- CAS No.152126-31-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Fluoropicolinic Acid (CAS 152126-31-3) designed for advanced pharmaceutical synthesis. Reliable supply with ≥99.0% purity for global research and production needs.
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Product Overview
3-Fluoropicolinic Acid represents a critical fluorinated heterocyclic building block extensively utilized in modern medicinal chemistry and organic synthesis. As a specialized pyridine derivative, this compound features a strategic fluorine substitution at the three-position of the pyridine ring, enhancing its metabolic stability and lipophilicity when incorporated into larger molecular structures. Our facility produces this intermediate under strict quality control protocols to ensure consistency for downstream pharmaceutical applications.
The introduction of fluorine atoms into organic molecules is a cornerstone strategy in contemporary drug design. This specific carboxylic acid derivative serves as a versatile precursor for constructing complex heterocyclic systems. Researchers and process chemists value this material for its reactivity profile, which allows for efficient coupling reactions and functional group transformations essential in multi-step synthesis pathways.
Key Chemical Properties
Understanding the physicochemical characteristics of 3-Fluoropicolinic Acid is vital for handling and processing. The compound exhibits a defined melting point and boiling point, indicating high thermal stability under standard processing conditions. The presence of the carboxylic acid group provides opportunities for amidation and esterification, while the fluorine substituent influences the electronic properties of the aromatic ring. These attributes make it an ideal candidate for developing novel therapeutic agents and agrochemical formulations.
- High thermal stability suitable for various reaction conditions
- Enhanced solubility profiles in common organic solvents
- Reactive carboxylic acid moiety for diverse derivatization
- Fluorine substitution for improved biological performance
Quality Specifications
We adhere to rigorous manufacturing standards to deliver material that meets or exceeds industry expectations. Each batch undergoes comprehensive analytical testing to verify identity, purity, and physical characteristics. The following table outlines the typical specifications for our commercial grade product:
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Fluoropicolinic Acid |
| CAS Number | 152126-31-3 |
| Molecular Formula | C6H4FNO2 |
| Molecular Weight | 141.10 g/mol |
| Appearance | White Powder |
| Purity | ≥99.0% |
| Melting Point | 154°C |
| Density | 1.105 g/cm3 |
Industrial Applications
Primarily utilized as a pharmaceutical intermediate, this compound plays a pivotal role in the synthesis of active pharmaceutical ingredients (APIs). It is frequently employed in the development of kinase inhibitors, receptor modulators, and other small molecule therapeutics where fluorinated pyridine scaffolds are required. Beyond human health applications, it also finds utility in the creation of advanced agrochemicals and specialty materials where specific electronic properties are necessary.
Storage and Handling
To maintain optimal quality, 3-Fluoropicolinic Acid should be stored in a tightly closed container within a cool, dry environment. Protection from moisture and direct sunlight is recommended to prevent degradation. Our packaging options include 25kg drums, designed for safe global transportation. We provide full documentation, including Certificates of Analysis (COA), to support regulatory compliance and quality assurance processes for our international partners.
