3-Fluoropyridine
- CAS No.372-47-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 3-Fluoropyridine (CAS 372-47-4) supplied as a colorless liquid for pharmaceutical intermediate synthesis. Global bulk availability with strict QC.
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Product Overview
3-Fluoropyridine represents a critical building block in modern organic synthesis, particularly within the pharmaceutical and agrochemical sectors. As a fluorinated heterocyclic compound, it offers unique reactivity profiles that enable the construction of complex molecular architectures. Our facility specializes in the production of high-grade 3-Fluoropyridine, ensuring consistent quality for research and industrial scaling. The introduction of fluorine atoms into pyridine rings significantly enhances metabolic stability and bioavailability in drug candidates, making this intermediate highly valuable for medicinal chemistry programs.
We maintain rigorous manufacturing standards to guarantee that every batch meets or exceeds international specifications. Our production process is optimized for yield and purity, minimizing impurities that could interfere with downstream reactions. Whether used for nucleophilic substitution or cross-coupling reactions, our product provides a reliable foundation for your synthesis pathways.
Key Specifications
Quality control is paramount in the supply of fine chemical intermediates. The following table outlines the typical physical and chemical properties associated with our standard grade material. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) to verify compliance.
| Parameter | Specification | Typical Result |
|---|---|---|
| CAS Number | 372-47-4 | 372-47-4 |
| Molecular Formula | C5H4FN | C5H4FN |
| Molecular Weight | 97.09 g/mol | 97.09 g/mol |
| Appearance | Colorless to light yellow liquid | Colorless liquid |
| Purity (GC) | ≥98.0% | ≥99.0% |
| Water Content | ≤0.5% | ≤0.2% |
| Boiling Point | 107-108 °C | 107.5 °C |
| Density | 1.13 g/mL at 25 °C | 1.13 g/mL |
Industrial Applications
The versatility of 3-Fluoropyridine extends across multiple high-value industries. Its primary application lies in the synthesis of active pharmaceutical ingredients (APIs), where the fluorine moiety serves as a key pharmacophore. Additionally, it is utilized in the development of advanced agrochemicals and functional materials.
- Pharmaceutical Intermediates: Used in the preparation of kinase inhibitors and receptor modulators.
- Agrochemical Synthesis: Serves as a precursor for novel herbicides and pesticides.
- Material Science: Employed in the creation of specialized polymers and liquid crystals.
- Research and Development: Essential reagent for organic chemistry laboratories exploring heterocyclic modifications.
Storage and Handling
Proper storage is essential to maintain the integrity of 3-Fluoropyridine. The product should be kept in tightly closed containers within a cool, dry, and well-ventilated area. It is sensitive to moisture and should be protected from strong oxidizing agents. Standard laboratory safety protocols apply, including the use of appropriate personal protective equipment (PPE) such as gloves and safety goggles during handling. Our packaging options include secure drums suitable for bulk transport, ensuring safety during global logistics operations. We adhere to all relevant transportation regulations for chemical goods.
