Intermediates

3-Fluoropyridine N-Oxide

  • CAS No.695-37-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Fluoropyridine N-Oxide designed for advanced pharmaceutical synthesis and organic chemistry applications.

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Product Technical Details

Product Overview

3-Fluoropyridine N-Oxide, systematically known as 3-fluoro-1-oxidopyridin-1-ium, represents a critical fluorinated heterocyclic building block within the modern pharmaceutical and agrochemical industries. As a specialized intermediate, this compound facilitates the introduction of both fluorine atoms and N-oxide functionalities into complex molecular architectures. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for research and development teams focused on novel drug discovery and process chemistry optimization.

The presence of the fluorine substituent at the third position of the pyridine ring significantly alters the electronic properties and metabolic stability of downstream products. This characteristic is highly valued in medicinal chemistry for enhancing bioavailability and binding affinity in target proteins. We supply this material with rigorous quality control standards to support large-scale production needs.

Key Specifications

Our production facility adheres to strict international quality management systems. Each batch undergoes comprehensive analytical testing to verify identity, purity, and physical properties. The following table outlines the standard technical specifications for our commercial grade material:

ParameterSpecification
Chemical Name3-Fluoro-1-oxidopyridin-1-ium
CAS Registry Number695-37-4
Molecular FormulaC5H4FNO
Molecular Weight113.09 g/mol
AppearanceWhite Crystalline Powder
Purity (HPLC)≥99.0%
Melting Point65-68°C
Boiling Point274.7°C at 760 mmHg
Density1.18 g/cm3
Flash Point119.9°C

Industrial Applications

This fluorinated pyridine derivative serves as a versatile precursor in the synthesis of various biologically active compounds. Its primary utility lies in the construction of pharmaceutical intermediates where specific substitution patterns are required. The N-oxide group can be utilized for further functionalization, including reduction to amines or participation in cycloaddition reactions. Furthermore, the chemical stability of the carbon-fluorine bond ensures that the fluorine label remains intact throughout multi-step synthesis routes.

Common application areas include the development of kinase inhibitors, anti-inflammatory agents, and central nervous system therapeutics. Process chemists value this material for its reliable reactivity profile and solubility characteristics in common organic solvents. We support our clients with technical data packages that assist in scaling reactions from laboratory benchtop to pilot plant operations.

Quality Assurance and Safety

Quality is the cornerstone of our chemical supply chain. Every drum shipped is accompanied by a Certificate of Analysis (COA) detailing the results of identity confirmation and purity assays. We employ advanced spectroscopic methods such as NMR and Mass Spectrometry to guarantee structural integrity. Our packaging ensures protection against moisture and contamination during transit.

Regarding safety, this compound should be handled in accordance with standard laboratory safety protocols for fine chemicals. It is recommended to use appropriate personal protective equipment, including gloves and eye protection, when handling the powder. Storage should be maintained in a cool, dry environment with containers tightly sealed to prevent exposure to atmospheric humidity. Our logistics team ensures compliant global shipping solutions for hazardous materials where applicable.

Why Choose Our Supply

As a dedicated manufacturer of fine chemical intermediates, we offer competitive bulk pricing without compromising on quality. Our supply chain is robust, ensuring timely delivery to meet your production schedules. We provide comprehensive technical support to assist with integration into your specific manufacturing processes. Partner with us for a reliable source of high-performance chemical building blocks.