Intermediates

3-Fluorotoluene

  • CAS No.352-70-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 3-Fluorotoluene (CAS 352-70-5) designed for advanced organic synthesis. Reliable supply with comprehensive quality documentation.

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Product Technical Details

Product Overview

3-Fluorotoluene is a premier fluorinated aromatic compound widely recognized for its versatility in modern chemical manufacturing. As a key building block, this meta-substituted toluene derivative plays an essential role in the development of complex molecular structures. Our facility produces this material using advanced fluorination technologies to ensure consistent quality and high purity levels suitable for demanding industrial applications.

The strategic placement of the fluorine atom at the meta position provides unique reactivity profiles compared to ortho or para isomers. This specific structural configuration makes it an invaluable precursor for pharmaceuticals, agrochemicals, and specialized functional materials. We maintain strict control over every batch to guarantee performance reliability in downstream synthesis processes.

Key Physical Properties

Understanding the physicochemical characteristics of 3-Fluorotoluene is vital for safe handling and process optimization. The compound exists as a clear liquid at standard conditions, facilitating easy pumping and metering in reactor systems. Its volatility and density profiles are well-suited for various distillation and extraction protocols commonly employed in fine chemical production.

PropertyValue
Molecular FormulaC7H7F
Molecular Weight110.129 g/mol
Density1.0 ± 0.1 g/cm3
Boiling Point118.2 ± 9.0 °C at 760 mmHg
Melting Point-87 °C
Flash Point9.4 ± 0.0 °C
Vapour Pressure20.1 ± 0.2 mmHg at 25°C
Index of Refraction1.477

Quality Specifications

Quality assurance is the cornerstone of our manufacturing philosophy. Each production lot undergoes rigorous analytical testing using gas chromatography and other validated methods. We prioritize the minimization of isomeric impurities, particularly 2-Fluorotoluene and 4-Fluorotoluene, to ensure the integrity of your final products. Our standard specification guarantees an assay of not less than 99.5 percent, exceeding typical industry requirements.

Items of AnalysisStandardTypical Results
AppearanceColorless transparent liquidConform
Assay (GC)≥ 99.5%99.79%
Toluene≤ 0.05%ND
2-Fluorotoluene≤ 0.05%0.04%
4-Fluorotoluene≤ 0.2%0.11%
Max Single Impurity≤ 0.1%0.02%

Industrial Applications

This fluorinated intermediate serves multiple critical functions across diverse chemical sectors. Its primary use lies in the synthesis of active pharmaceutical ingredients where fluorine substitution enhances metabolic stability and bioavailability. Additionally, it is utilized in the production of high-performance polymers and liquid crystals. The compound also acts as a vital coupling partner in cross-coupling reactions, enabling the construction of biaryl systems.

  • Pharmaceutical intermediate for drug discovery
  • Agrochemical synthesis precursor
  • Material science and polymer modification
  • Liquid crystal display components
  • Fine chemical custom synthesis

Storage and Handling

Proper storage conditions are essential to maintain product stability over time. We recommend keeping containers tightly closed in a cool, ventilated area away from direct sunlight and heat sources. The material should be protected from moisture and strong oxidizing agents. Our packaging options include 200 kg drums, with flexible customization available to meet specific logistical requirements. Comprehensive safety data sheets and certificates of analysis are provided with every shipment to support regulatory compliance.