Intermediates

3-Formylphenylboronic acid

  • CAS No.87199-16-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Formylphenylboronic acid (CAS 87199-16-4) designed for pharmaceutical intermediate synthesis. Reliable supply with comprehensive quality documentation.

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Product Technical Details

Product Overview

3-Formylphenylboronic acid is a specialized organic compound widely recognized for its utility in modern medicinal chemistry and organic synthesis. As a key boronic acid derivative, this substance serves as a critical building block in the construction of complex molecular architectures. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and industrial-scale production environments.

This chemical features a formyl group positioned at the meta position relative to the boronic acid moiety on the phenyl ring. This specific structural arrangement provides unique reactivity profiles that are highly valued in cross-coupling reactions. We maintain strict control over every batch to guarantee performance reliability for our global partners.

Chemical Properties and Stability

Understanding the physicochemical characteristics of 3-Formylphenylboronic acid is essential for safe handling and optimal usage. The compound presents as a grayish white crystalline solid under standard conditions. It exhibits moderate stability but should be protected from excessive moisture and strong oxidizing agents to maintain integrity.

The molecular structure allows for versatile functionalization, particularly through the boronic acid group which facilitates carbon-carbon bond formation. Proper storage in a cool, dry, and well-ventilated area is recommended to prevent degradation. Always keep containers tightly closed when not in use to minimize exposure to atmospheric humidity.

Industrial Applications

The primary application of this material lies within the pharmaceutical sector, specifically as an intermediate in the synthesis of active pharmaceutical ingredients. It is notably utilized in the production pathway for specialized therapeutic agents such as Fasiglifam. The versatility of the boronic acid functionality enables its use in Suzuki-Miyaura coupling reactions, which are foundational in creating biaryl structures common in drug molecules.

  • Pharmaceutical intermediate synthesis
  • Suzuki-Miyaura cross-coupling reactions
  • Organic building block for complex molecules
  • Research and development in medicinal chemistry
  • Custom synthesis projects requiring high purity

Quality Specifications

We adhere to rigorous quality assurance protocols to ensure that every shipment meets the highest industry standards. Our analytical teams utilize advanced instrumentation including HPLC and NMR to verify composition and purity. The following table outlines the typical specifications for our commercial grade product.

ParameterSpecification
CAS Number87199-16-4
Molecular FormulaC7H7BO3
Molecular Weight149.94 g/mol
AppearanceGrayish white crystal
Assay (Purity)≥98.0%
Water Content≤0.50%
Melting Point182-186 °C
Storage ConditionCool, dry, ventilated place

Safety and Handling

Safety is our top priority during the production and transport of chemical materials. This product is classified under transport hazard class 8 and should be handled with appropriate personal protective equipment. Users are advised to consult the Material Safety Data Sheet (MSDS) for detailed hazard information and emergency measures.

We offer flexible packaging options including 25kg drums, with custom configurations available upon request. Our logistics network ensures timely global delivery while maintaining compliance with international shipping regulations for corrosive solids. Contact our technical sales team for detailed documentation including Certificates of Analysis and manufacturing process details.