Intermediates

(3-(Hydroxymethyl)-4-methoxyphenyl)boronic acid

  • CAS No.908142-03-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity (3-(Hydroxymethyl)-4-methoxyphenyl)boronic acid designed for advanced organic synthesis and Suzuki coupling reactions. Reliable industrial supply with full COA.

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Product Technical Details

Product Overview

(3-(Hydroxymethyl)-4-methoxyphenyl)boronic acid is a specialized organic building block extensively utilized in modern medicinal chemistry and materials science. As a key boronic acid derivative, this compound features a unique substitution pattern with both hydroxymethyl and methoxy functional groups on the phenyl ring. This specific structural configuration enhances its reactivity profile, making it an ideal candidate for palladium-catalyzed cross-coupling reactions. Our manufacturing process ensures consistent quality suitable for scaling from laboratory research to industrial production.

In the realm of complex molecule synthesis, this boronic acid serves as a critical nucleophilic partner. The presence of the methoxy group provides electronic modulation, while the hydroxymethyl moiety offers a handle for further functionalization. This dual functionality allows chemists to construct diverse biaryl structures efficiently. We prioritize strict quality control measures to guarantee that every batch meets the rigorous demands of pharmaceutical and agrochemical development pipelines.

Key Specifications

Our production facility adheres to international quality management standards. Each lot undergoes comprehensive analytical testing to verify identity, purity, and physical properties. The following table outlines the typical specifications for this product based on our factory standard analysis.

Items of AnalysisStandard of AnalysisTest Results
AppearanceWhite solidConform
Assay (HPLC)≥98.0%98.77%
Molecular FormulaC8H11BO4Conform
Molecular Weight181.98 g/molConform
ConclusionConforms to Factory Standard

Industrial Applications

This compound is primarily employed as an intermediate in the synthesis of advanced pharmaceutical APIs and fine chemicals. Its primary application lies in Suzuki-Miyaura coupling reactions, where it couples with aryl or vinyl halides to form carbon-carbon bonds. This methodology is foundational in the production of various therapeutic agents, including kinase inhibitors and anti-inflammatory drugs.

  • Pharmaceutical Intermediate: Used in the construction of complex drug molecules requiring biaryl scaffolds.
  • Agrochemical Synthesis: Employed in the development of novel pesticides and herbicides with improved environmental profiles.
  • Materials Science: Utilized in the creation of organic electronic materials and polymers with specific optical properties.
  • Research and Development: Essential reagent for academic and industrial labs focusing on organic methodology.

Quality Assurance and Storage

We understand that stability is crucial for boronic acid derivatives. Our packaging is designed to protect the product from moisture and oxidation, which can lead to deboronation. We recommend storing this material in a cool, dry place away from direct sunlight. Proper storage ensures the longevity of the reagent and maintains its reactivity for future synthesis campaigns. Every shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified parameters.

As a global manufacturer, we are committed to providing reliable supply chains for our B2B partners. Whether you require bulk quantities for large-scale manufacturing or smaller batches for process development, our logistics team ensures timely delivery. Contact our technical sales team for detailed information regarding pricing, lead times, and custom synthesis capabilities tailored to your specific project requirements.