Intermediates

3-Hydroxyphenylboronic acid

  • CAS No.87199-18-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 3-Hydroxyphenylboronic acid (CAS 87199-18-6) designed for pharmaceutical synthesis. High purity >=98.0% ensures reliable reaction outcomes.

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Product Technical Details

Product Overview

3-Hydroxyphenylboronic acid is a highly valued organoboron compound widely utilized in modern organic synthesis and medicinal chemistry. As a key building block, this substance features a hydroxy group at the meta position of the phenyl ring, which significantly influences its reactivity and solubility profiles. Our manufacturing facility produces this chemical under strict quality control standards to ensure consistency across batches for industrial and research applications.

This compound serves as a critical precursor in the development of complex pharmaceutical agents. The presence of the boronic acid moiety enables versatile transformation pathways, making it indispensable for chemists designing novel therapeutic molecules. We prioritize the delivery of high-purity materials to support efficient downstream processing.

Technical Specifications

ParameterValue
Chemical Name3-Hydroxyphenylboronic acid
CAS Number87199-18-6
Molecular FormulaC6H7BO3
Molecular Weight137.93 g/mol
AppearanceWhite powder
Assay≥98.0%
Water Content≤0.50%
Melting Point210-213 °C (dec.)
Density1.32 g/cm3

Industrial Applications

The primary application of 3-Hydroxyphenylboronic acid lies in its role as a pharmaceutical intermediate. It is extensively employed in Suzuki-Miyaura cross-coupling reactions, which are fundamental for constructing carbon-carbon bonds in biaryl systems. This capability is essential for synthesizing active pharmaceutical ingredients (APIs) used in treating various diseases.

Beyond pharmaceuticals, this chemical finds utility in material science and agrochemical development. Its stability and reactivity profile allow for integration into diverse synthetic routes. Researchers value this compound for its ability to facilitate selective transformations while maintaining structural integrity under standard reaction conditions.

Quality Assurance and Advantages

  • High purity levels ensuring minimal impurity interference in sensitive reactions.
  • Strict quality control protocols including HPLC and NMR verification.
  • Consistent batch-to-batch reproducibility for large-scale manufacturing.
  • Comprehensive documentation including Certificate of Analysis (COA).
  • Optimized packaging to maintain stability during transit and storage.

Packaging and Storage

We offer flexible packaging solutions to meet diverse customer requirements. Standard packaging includes 25kg drums, which are designed to protect the product from moisture and physical damage. Custom packaging configurations are available upon request to align with specific logistical needs.

For optimal preservation, store this product in a cool, dry, and well-ventilated area. Ensure containers remain tightly closed when not in use to prevent exposure to atmospheric moisture. The product is classified as non-dangerous goods for transport, simplifying logistics and handling procedures globally.