Intermediates

3-Hydroxypyrazine-2-carboxamide

  • CAS No.55321-99-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Hydroxypyrazine-2-carboxamide is a critical pharmaceutical intermediate used primarily in the synthesis of antiviral agents like Fapilavir.

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Product Technical Details

Product Overview

3-Hydroxypyrazine-2-carboxamide represents a vital heterocyclic building block within the modern pharmaceutical landscape. This specialized chemical compound is characterized by its pyrazine ring structure substituted with hydroxyl and carboxamide functional groups. As a key intermediate, it plays an indispensable role in the multi-step synthesis of advanced antiviral therapeutics. Our facility produces this material under strict quality control protocols to ensure consistency and reliability for downstream pharmaceutical manufacturing processes.

The molecular structure of this pyrazine derivative offers unique reactivity profiles that are essential for constructing complex medicinal molecules. Researchers and process chemists value this intermediate for its stability and predictable behavior during coupling reactions. We understand the critical nature of supply chain continuity in the pharmaceutical industry, which is why we maintain robust production capabilities to meet global demand without compromise.

Technical Specifications

ParameterValue
Chemical Name3-Hydroxypyrazine-2-carboxamide
CAS Number55321-99-8
Molecular FormulaC5H5N3O2
Molecular Weight139.112 g/mol
AppearanceWhite to off-white crystalline powder
Assay (Purity)≥98.0%
Melting Pointca 270°C
Density1.5±0.1 g/cm3
Storage ConditionsCool, ventilated place

Industrial Applications

The primary application of 3-Hydroxypyrazine-2-carboxamide lies in the synthesis of novel antiviral medications. It serves as a crucial precursor in the manufacturing route of Fapilavir, an important agent in the treatment of influenza viruses. The high purity standards required for this intermediate ensure that the final active pharmaceutical ingredient meets rigorous regulatory compliance for safety and efficacy.

  • Essential building block for antiviral drug synthesis
  • Used in research and development of new pyrazine-based therapeutics
  • Supports large-scale commercial manufacturing of pharmaceutical intermediates
  • Compatible with various organic synthesis pathways requiring heterocyclic amines

Quality Assurance and Storage

Quality is the cornerstone of our manufacturing philosophy. Every batch of 3-Hydroxypyrazine-2-carboxamide undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment to guarantee transparency and traceability. Proper storage is essential to maintain the integrity of the chemical structure over time.

We recommend storing this product in a cool, dry, and well-ventilated area away from direct sunlight and moisture. The packaging is designed to protect the material from environmental contaminants during transit. Our logistics team ensures that all shipments are handled according to international chemical safety standards. For bulk orders, we offer flexible packaging solutions including 25 kg drums or customized configurations based on specific client requirements. Our technical support team is available to assist with synthesis optimization and application guidance.