3-Methyl-6-nitroindazole

Product Overview

3-Methyl-6-nitroindazole represents a critical heterocyclic building block within the modern pharmaceutical landscape. As a specialized nitro-substituted indazole derivative, this compound serves as an essential precursor in the development of advanced therapeutic agents. Our facility produces this chemical under rigorous quality control standards to ensure consistency and reliability for downstream synthetic applications. The molecular structure provides a stable platform for further functionalization, making it a preferred choice for process chemistry teams working on complex organic synthesis projects.

Physical and Chemical Properties

This compound is characterized by its distinct yellow powder appearance, indicating high chemical purity and proper crystallization during manufacturing. The substance exhibits robust thermal stability with a melting point range between 187 and 188 degrees Celsius. Its molecular formula, C8H7N3O2, corresponds to a molecular weight of approximately 177.16 g/mol. The density is measured at 1.4 plus or minus 0.1 g/cm3, ensuring predictable handling characteristics during weighing and transfer operations. Additionally, the boiling point is recorded at 384.9 plus or minus 22.0 degrees Celsius at 760 mmHg, while the flash point remains at 186.6 plus or minus 22.3 degrees Celsius, requiring standard safety precautions during storage and transport.

Quality Specifications

We maintain strict adherence to international quality standards to guarantee performance in sensitive synthetic routes. Each batch undergoes comprehensive analysis to verify compliance with factory specifications. The following table outlines the key parameters verified during our quality control process:

Industrial Applications

The primary application of 3-Methyl-6-nitroindazole lies in the pharmaceutical intermediate sector. It is specifically utilized as a key starting material in the synthesis of Pazopanib, a known kinase inhibitor used in oncology treatments. The nitro group and methyl substitution pattern allow for selective reduction and coupling reactions necessary for constructing the final active pharmaceutical ingredient. Our production process is optimized to minimize impurities that could interfere with subsequent catalytic steps, ensuring higher yields for our clients. This material is suitable for large-scale manufacturing environments where batch-to-batch consistency is paramount.

Storage and Packaging

To maintain product integrity, 3-Methyl-6-nitroindazole should be stored in a cool, ventilated place away from direct sunlight and moisture sources. We offer flexible packaging solutions to meet diverse logistical requirements, with standard packing available in 25 kg drums. Custom packaging configurations can be arranged according to specific customer requirements to facilitate easier handling and integration into your supply chain. Our global manufacturing network ensures timely delivery and comprehensive documentation, including Certificates of Analysis (COA) for every shipment. Partner with us for reliable access to high-quality chemical intermediates supported by decades of industry expertise.