Intermediates

3-Methylbenzotrifluoride

  • CAS No.401-79-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Methylbenzotrifluoride (CAS 401-79-6) designed for pharmaceutical synthesis. Reliable supply with ≥99.0% purity for industrial applications.

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Product Technical Details

Product Overview

3-Methylbenzotrifluoride is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Known chemically as 1-methyl-3-(trifluoromethyl)benzene, this substance is characterized by the presence of a trifluoromethyl group attached to a benzene ring, which significantly enhances its lipophilicity and metabolic stability. These properties make it an invaluable precursor in the development of advanced pharmaceutical agents and agrochemical formulations. Our facility produces this compound under strict quality control standards to ensure consistency and reliability for downstream manufacturing processes.

As a leading global manufacturer, we understand the demanding requirements of the fine chemical industry. Our production capabilities are designed to deliver bulk quantities without compromising on molecular integrity. The introduction of fluorine atoms into organic molecules is a strategic move in medicinal chemistry to improve bioavailability and binding affinity. Therefore, securing a stable supply of high-quality fluorinated intermediates like 3-Methylbenzotrifluoride is essential for research and development teams aiming to innovate within therapeutic areas.

Technical Specifications

ParameterSpecification
Chemical Name3-Methylbenzotrifluoride
CAS Number401-79-6
Molecular FormulaC8H7F3
Molecular Weight160.14 g/mol
AppearanceColorless to Pale Yellow Liquid
Purity≥99.0%
Boiling Point130 °C (lit.)
Density1.148 g/cm3
Refractive Index1.427
Flash Point80 °F

Industrial Applications

This fluorinated intermediate is primarily utilized in the synthesis of complex pharmaceutical active ingredients. The trifluoromethyl group is a key pharmacophore in many modern drugs, influencing the electronic properties of the molecule and enhancing its resistance to metabolic degradation. Consequently, 3-Methylbenzotrifluoride is frequently employed in the production of anti-inflammatory agents, cardiovascular medications, and central nervous system therapeutics. Beyond pharmaceuticals, it finds application in the agrochemical sector for creating robust pesticides and herbicides that require high environmental stability.

Chemists value this compound for its reactivity in various coupling reactions, including cross-coupling and nucleophilic substitutions. Its versatility allows for the construction of diverse chemical libraries during the drug discovery phase. By providing a reliable source of this material, we support the acceleration of pipeline development for our partners. Whether used in small-scale laboratory research or large-scale commercial production, our product meets the rigorous demands of industrial chemistry.

Quality Assurance and Advantages

  • Consistent High Purity: Guaranteed ≥99.0% purity to minimize side reactions.
  • Advanced Manufacturing: Produced using state-of-the-art fluorination technology.
  • Comprehensive Documentation: Full COA and MSDS provided with every shipment.
  • Global Logistics: Efficient packaging and shipping solutions for international clients.
  • Technical Support: Dedicated team available for synthesis route optimization.

Storage and Handling

To maintain the integrity of 3-Methylbenzotrifluoride, proper storage conditions are essential. The product should be stored in a clean, cool, and dry area, strictly kept away from moisture and strong direct light or heat sources. Containers must remain tightly sealed when not in use to prevent contamination or evaporation. Safety protocols recommend handling this chemical in a well-ventilated environment with appropriate personal protective equipment. Our packaging options include 25kg drums, designed to ensure safety during transit and ease of handling in warehouse environments. We are committed to delivering not just a chemical product, but a partnership built on safety, quality, and performance.