3-Nitro-5-(Trifluoromethyl)Benzoic Acid
- CAS No.328-80-3
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
High-purity 3-Nitro-5-(Trifluoromethyl)Benzoic Acid (CAS 328-80-3) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical manufacturing.
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Product Overview
3-Nitro-5-(Trifluoromethyl)Benzoic Acid is a highly specialized fluorinated organic intermediate that plays a pivotal role in modern chemical synthesis. Identified by CAS number 328-80-3, this compound features a benzoic acid backbone substituted with both nitro and trifluoromethyl groups. These functional groups impart unique electronic and steric properties that make the molecule an invaluable building block for complex organic transformations. Our facility produces this chemical under stringent quality management systems to ensure consistency and reliability for downstream applications.
The introduction of the trifluoromethyl group significantly enhances the lipophilicity and metabolic stability of resulting compounds, which is a critical consideration in medicinal chemistry and agrochemical development. As a key intermediate, it serves as a precursor for various pharmaceutical agents and functional materials. We understand the critical nature of supply chain stability for research and production teams, which is why we maintain robust inventory levels and efficient logistics protocols to support global demand.
Key Specifications
Quality assurance is the cornerstone of our manufacturing process. Each batch of 3-Nitro-5-(Trifluoromethyl)Benzoic Acid undergoes rigorous analytical testing to verify compliance with established specifications. The following table outlines the standard physical and chemical parameters guaranteed for our commercial grade product.
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Nitro-5-(Trifluoromethyl)Benzoic Acid |
| CAS Number | 328-80-3 |
| Molecular Formula | C8H4F3NO4 |
| Molecular Weight | 235.12 g/mol |
| Appearance | Off-white to pale yellow powder |
| Assay (Purity) | ≥98.0% |
| Moisture Content | ≤0.2% |
| Melting Point | 128°C |
| Density | 1.464 g/cm3 |
Industrial Applications
This fluorinated benzoic acid derivative is extensively utilized across multiple high-value industries. In the pharmaceutical sector, it acts as a crucial synthon for developing novel drug candidates where metabolic stability is required. The electron-withdrawing nature of the nitro and trifluoromethyl groups facilitates various nucleophilic substitution reactions and reduction processes, enabling chemists to construct diverse molecular architectures.
Furthermore, the compound finds application in the agrochemical industry for the synthesis of advanced herbicides and pesticides. The presence of fluorine atoms often improves the biological activity and environmental profile of agricultural chemicals. Beyond life sciences, this intermediate is also explored in material science for creating polymers with enhanced thermal and chemical resistance. Our technical team can provide detailed synthesis route guidance and support for custom manufacturing requirements tailored to specific project needs.
Storage and Handling
To maintain optimal quality, 3-Nitro-5-(Trifluoromethyl)Benzoic Acid should be stored in a cool, ventilated area away from direct sunlight and moisture. The standard packaging consists of 25 kg drums, though we offer flexible packaging solutions to accommodate specific customer requirements. Proper handling procedures include using appropriate personal protective equipment to prevent inhalation or skin contact. We provide comprehensive documentation including Certificates of Analysis (COA) and Safety Data Sheets (SDS) with every shipment to ensure regulatory compliance and safe usage in your laboratory or production facility.
