Intermediates

3-Nitrophthalic Acid

  • CAS No.603-11-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Nitrophthalic Acid (CAS 603-11-2) designed for pharmaceutical synthesis. Reliable supply with strict quality control for global industrial applications.

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Product Technical Details

Product Overview

3-Nitrophthalic Acid stands as a pivotal compound within the landscape of advanced organic synthesis and pharmaceutical manufacturing. As a nitrated derivative of phthalic acid, this chemical building block possesses unique reactivity profiles that make it indispensable for constructing complex molecular architectures. Our facility specializes in the production of this key intermediate, ensuring that every batch meets rigorous international standards for purity and consistency.

The compound is characterized by its stable nitro group positioned on the benzene ring, which facilitates various downstream chemical transformations. These transformations are critical in the development of active pharmaceutical ingredients (APIs) and specialized functional materials. We understand that in the competitive pharmaceutical sector, the quality of raw materials directly influences the efficacy and safety of the final therapeutic products. Therefore, our production protocols are designed to minimize impurities and maximize yield.

Technical Specifications

To guarantee performance in sensitive synthesis reactions, we maintain strict control over physical and chemical parameters. The following table outlines the standard specifications for our commercial grade 3-Nitrophthalic Acid. Custom specifications may be available upon request for specific research or production needs.

ParameterSpecification
AppearanceYellowish powder
Purity (HPLC)≥99.0%
4-Nitrophthalic Acid Impurity≤0.5%
Moisture Content≤0.3%
Chloride (Titrimetry)≤50 ppm
Sulfate<200 ppm
Nitrate<100 ppm
Molecular FormulaC8H5NO6
Molecular Weight211.13 g/mol
Melting Point210 °C (dec.)

Industrial Applications

The primary utility of 3-Nitrophthalic Acid lies in its role as a precursor for high-value pharmaceutical intermediates. It is extensively utilized in the synthesis pathway of immunomodulatory agents, such as Pomalidomide derivatives. The nitro group serves as a versatile handle for reduction to amines or other functional group interconversions required in multi-step synthesis routes.

Beyond pharmaceuticals, this chemical finds application in the development of specialized polymers and dyes where specific electronic properties are required. Our clients value our material for its consistent performance in reaction scales ranging from laboratory research to full-scale industrial production. We support process development teams with reliable data and material safety documentation to streamline regulatory filings.

Quality Assurance and Logistics

Quality assurance is embedded in every stage of our manufacturing process. From raw material sourcing to final packaging, each lot undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with every shipment, verifying compliance with the specified parameters. Our quality control laboratories are equipped with modern instrumentation to detect trace impurities that could affect downstream processing.

For logistics, we offer flexible packaging solutions to suit various operational requirements. Standard packaging includes 25kg cardboard drums, which are designed to protect the product from moisture and physical damage during transit. Larger bulk quantities can be arranged according to customer specifications. Storage recommendations include keeping the container tightly closed in a cool, dry, and well-ventilated area, away from strong light and heat sources to maintain stability.

We are committed to being a reliable global partner for chemical sourcing. Our supply chain is robust, ensuring timely delivery to support your production schedules. For technical inquiries, custom synthesis requests, or bulk pricing information, our sales and support team is ready to assist you in optimizing your procurement strategy.