Intermediates

3-Nitrophthalic Anhydride

  • CAS No.641-70-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Nitrophthalic Anhydride (CAS 641-70-3) designed for pharmaceutical synthesis. Reliable supply with strict quality control for advanced organic intermediates.

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Product Technical Details

Product Overview

3-Nitrophthalic Anhydride is a critical nitro-substituted aromatic compound widely recognized for its versatility in organic synthesis and pharmaceutical manufacturing. As a key building block, this chemical facilitates the construction of complex heterocyclic systems essential for developing advanced therapeutic agents. Our facility produces this intermediate under stringent quality management systems to ensure consistency and reliability for global industrial partners.

The compound features a phthalic anhydride backbone with a nitro group at the third position, imparting unique reactivity profiles suitable for nucleophilic substitution and condensation reactions. This specific structural configuration makes it an invaluable precursor in the synthesis of various bioactive molecules and specialized polymers.

Technical Specifications

We adhere to rigorous analytical standards to guarantee the performance of our chemical products. The following table outlines the key physical and chemical parameters verified during our quality control process.

ParameterSpecification
CAS Number641-70-3
Molecular FormulaC8H3NO5
Molecular Weight193.11 g/mol
AppearanceWhite Crystalline Powder
Purity≥98.0%
Melting Point163-165 °C
Loss on Drying≤0.5%
Density1.687 g/cm3

Industrial Applications

This intermediate serves a pivotal role in the pharmaceutical sector, particularly in the synthesis of immunomodulatory pharmaceutical agents and other specialized APIs. Its high reactivity allows for efficient coupling reactions, making it a preferred choice for process chemistry teams aiming for high yield and minimal byproduct formation.

Beyond pharmaceuticals, 3-Nitrophthalic Anhydride is utilized in the production of high-performance polymers and dyes. The nitro group provides a handle for further functionalization, enabling chemists to tailor material properties for specific industrial requirements. Whether used in laboratory-scale research or large-scale manufacturing, this compound delivers consistent performance.

Quality Assurance and Safety

Our commitment to quality extends beyond mere specification compliance. Each batch undergoes comprehensive testing using advanced chromatography and spectroscopy methods to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment to ensure full transparency and traceability.

Regarding safety and handling, this product should be stored in a cool, dry, and well-ventilated area away from moisture and strong light. Proper personal protective equipment, including gloves and eye protection, is recommended during handling to prevent irritation. We offer flexible packaging options, including 25kg cardboard drums, customized to meet specific logistical requirements while maintaining product integrity during transit.