3-Pyridylboronic Acid
- CAS No.1692-25-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Pyridylboronic Acid (CAS 1692-25-7) designed for efficient Suzuki coupling reactions and pharmaceutical intermediate synthesis.
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Product Overview
3-Pyridylboronic Acid represents a cornerstone molecule in modern organic synthesis, specifically within the realm of heterocyclic chemistry. As a vital organoboron compound, this substance serves as an essential building block for constructing complex pharmaceutical architectures. Our manufacturing facility produces this chemical with stringent quality controls to ensure consistent performance in catalytic cross-coupling reactions. The compound is characterized by its stability and reactivity profile, making it a preferred choice for process chemists developing new therapeutic agents.
We understand that reproducibility is critical in drug discovery and development. Therefore, every batch of 3-Pyridylboronic Acid undergoes rigorous analytical testing. This commitment to quality ensures that downstream synthesis steps proceed without unexpected impurities or yield losses. Our production capabilities are scaled to meet both research-scale requirements and large-scale commercial manufacturing demands.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 1692-25-7 |
| Molecular Formula | C5H6BNO2 |
| Molecular Weight | 122.92 g/mol |
| Appearance | White Powder |
| Assay (Purity) | ≥98.0% |
| Water Content | ≤0.50% |
| Melting Point | >300 °C |
| Density | 1.22 g/cm3 |
Industrial Applications
The primary application of 3-Pyridylboronic Acid lies in its utility as a coupling partner in Suzuki-Miyaura reactions. This palladium-catalyzed cross-coupling process is fundamental in forming carbon-carbon bonds, particularly when linking pyridine rings to other aromatic or heteroaromatic systems. Such transformations are ubiquitous in the synthesis of kinase inhibitors, antiviral agents, and other bioactive small molecules.
Beyond pharmaceuticals, this boronic acid derivative finds use in materials science and agrochemical development. Its ability to participate in diverse chemical transformations allows chemists to explore broad chemical space efficiently. The high purity level we maintain minimizes the risk of catalyst poisoning, which is a common concern when using lower-grade boronic acids in sensitive catalytic cycles.
- Optimized for Suzuki-Miyaura cross-coupling reactions
- Suitable for heterocyclic pharmaceutical intermediate synthesis
- Consistent batch-to-batch reproducibility for scale-up
- Low water content ensures enhanced stability during storage
Quality Assurance and Safety
Quality assurance is integral to our operation. We employ advanced spectroscopic methods, including NMR and HPLC, to verify the identity and purity of each lot. A Certificate of Analysis (COA) is provided with every shipment, detailing the specific test results for your quality records. This transparency supports regulatory compliance and facilitates smooth technology transfer processes.
Regarding safety, 3-Pyridylboronic Acid is classified as non-dangerous goods for transport under standard conditions. However, standard laboratory safety practices should always be observed. The material should be handled in a well-ventilated environment to avoid inhalation of dust. Personal protective equipment, including gloves and safety goggles, is recommended during handling procedures.
Storage and Packaging
To maintain optimal quality, this product should be stored in a cool, dry place. Containers must remain tightly closed to prevent moisture absorption, as boronic acids can undergo protodeboronation or anhydride formation upon prolonged exposure to humidity. We offer flexible packaging solutions, typically supplying in 25kg drums, but custom packaging configurations are available to suit specific logistical requirements. Our global shipping network ensures timely delivery to research centers and manufacturing plants worldwide.
