3-Quinuclidinone Hydrochloride
- CAS No.1193-65-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Quinuclidinone Hydrochloride (CAS 1193-65-3) designed for pharmaceutical synthesis, specifically serving as a critical precursor for Solifenacin and Palonosetron production.
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Product Overview
3-Quinuclidinone Hydrochloride is a highly specialized organic compound recognized for its pivotal role in modern pharmaceutical chemistry. As a stable hydrochloride salt of the quinuclidine ketone structure, this material serves as an essential building block in the synthesis of complex therapeutic agents. Our manufacturing process ensures exceptional molecular integrity, making it an ideal choice for research and development teams focused on urological and antiemetic medication pathways. The compound is characterized by its robust chemical stability and high reactivity in nucleophilic substitution reactions, which are critical for constructing advanced pharmacophores.
Technical Specifications
We adhere to strict quality control protocols to guarantee consistency across every batch. The following parameters reflect our standard commercial grade specifications, which can be customized upon request for specific synthetic routes.
| Parameter | Specification |
|---|---|
| CAS Number | 1193-65-3 |
| Molecular Formula | C7H12ClNO |
| Molecular Weight | 161.63 g/mol |
| Appearance | White Powder |
| Purity (HPLC) | ≥99.0% |
| Loss on Drying | ≤0.5% |
| Melting Point | >300 °C (dec.) |
Pharmaceutical Applications
This intermediate is primarily utilized in the multi-step synthesis of active pharmaceutical ingredients (APIs). Notably, it acts as a key precursor in the production of Solifenacin succinate, a widely prescribed medication for the management of overactive bladder symptoms. Furthermore, it is integral to the manufacturing process of Palonosetron, a second-generation 5-HT3 receptor antagonist used to prevent nausea and vomiting associated with chemotherapy. The high purity levels we maintain are crucial for minimizing impurities in the final drug substance, ensuring compliance with stringent regulatory standards such as ICH guidelines.
Quality Assurance and Storage
Our facility operates under rigorous quality management systems to preserve the chemical properties of 3-Quinuclidinone Hydrochloride. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing batch-specific test results. To maintain optimal stability, the product should be stored in tightly closed containers within a cool, dry, and well-ventilated area. The recommended storage temperature ranges between 2 °C and 8 °C, although short-term exposure to ambient conditions during transit is generally acceptable given its stable hydrochloride form. We recommend keeping the material away from incompatible substances such as strong oxidizing agents.
Global Supply and Logistics
As a dedicated manufacturer, we offer flexible packaging solutions to meet the diverse needs of our global clientele. Standard packaging includes 25kg cardboard drums, but we can accommodate custom requirements based on project scale. Our logistics network ensures timely delivery while maintaining chain-of-custody documentation for regulatory compliance. Whether you require bulk quantities for industrial scale-up or smaller batches for process development, our team provides technical support to optimize your synthesis route. Contact us today for current bulk pricing and availability.
