3-t-Butoxycarbonylphenylboronic acid
- CAS No.220210-56-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-t-Butoxycarbonylphenylboronic acid (CAS 220210-56-0) designed for advanced pharmaceutical synthesis. Reliable supply with COA.
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Product Overview
3-t-Butoxycarbonylphenylboronic acid is a specialized organic compound widely recognized for its utility in modern medicinal chemistry and pharmaceutical synthesis. As a protected boronic acid derivative, this molecule features a tert-butoxycarbonyl (Boc) group at the meta-position of the phenyl ring, providing essential stability and reactivity control during complex multi-step synthesis routes. Our manufacturing process ensures high chemical integrity, making it an ideal choice for researchers and industrial producers focused on developing advanced therapeutic agents.
This building block is particularly valued for its compatibility with palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling. The presence of the Boc protecting group allows for selective functionalization while preventing unwanted side reactions at the amine or acid sites during intermediate stages. We supply this material with strict quality controls to support scalable production environments. The chemical structure offers a balance between reactivity and stability, which is crucial for maintaining yield efficiency in large-scale manufacturing processes.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 220210-56-0 |
| Molecular Formula | C11H15BO4 |
| Molecular Weight | 222.05 g/mol |
| Purity (Assay) | ≥98.0% |
| Appearance | White or off-white solid powder |
| Melting Point | 96-102°C |
| Water Content | ≤0.50% |
| Density | 1.15 g/cm3 |
| Boiling Point | 375°C at 760 mmHg |
Industrial Applications
The primary application of 3-t-Butoxycarbonylphenylboronic acid lies in the construction of biaryl structures found in numerous pharmaceutical active ingredients. Its robust chemical profile supports various synthetic transformations required in the discovery and development of new drugs. Companies utilizing this intermediate benefit from its reliable performance in catalytic cycles, ensuring consistent yields and reduced purification burdens. Furthermore, the compound serves as a versatile precursor in the synthesis of kinase inhibitors and other targeted therapies where precise structural alignment is mandatory.
- Pharmaceutical intermediate synthesis for small molecule drugs.
- Key reagent in Suzuki-Miyaura cross-coupling reactions.
- Building block for complex organic frameworks and heterocycles.
- Utilized in medicinal chemistry research and development pipelines.
- Supports the production of neurology and oncology therapeutic candidates.
Quality Assurance and Storage
We adhere to rigorous quality management systems to guarantee the consistency of every batch. Each shipment is accompanied by a Certificate of Analysis (COA) verifying purity, identity, and physical constants. Our facility employs advanced analytical techniques including HPLC and NMR to confirm structural integrity. To maintain optimal stability, the product should be stored in a cool, dry, and well-ventilated area with containers tightly sealed to prevent moisture absorption. Hygroscopic nature requires careful handling to preserve assay levels over time. We offer flexible packaging options, including 25kg drums, tailored to meet specific logistical requirements for global distribution. Our supply chain is optimized for timely delivery to support continuous manufacturing operations without interruption.
