Intermediates

3-(Trifluoromethoxy)benzaldehyde

  • CAS No.52771-21-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-(Trifluoromethoxy)benzaldehyde (CAS 52771-21-8) supplied for advanced organic synthesis. Reliable bulk availability with strict QC standards.

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Product Technical Details

Product Overview

3-(Trifluoromethoxy)benzaldehyde is a specialized fluorinated organic intermediate characterized by the presence of a trifluoromethoxy group at the meta position of the benzaldehyde ring. This unique structural configuration imparts distinct electronic and steric properties, making it a highly valuable building block in modern medicinal chemistry and agrochemical development. Our facility produces this compound under stringent quality control protocols to ensure consistency across large-scale batches.

The introduction of the trifluoromethoxy moiety often enhances the metabolic stability and lipophilicity of downstream pharmaceutical candidates. As a result, this aldehyde derivative is frequently utilized in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). We commit to providing a reliable supply chain for research institutions and industrial manufacturers seeking high-performance chemical raw materials.

Technical Specifications

Our production process emphasizes high purity and minimal impurity profiles to facilitate efficient downstream reactions. The following table outlines the key physical and chemical parameters verified by our quality assurance team.

ParameterSpecification
Chemical Name3-(Trifluoromethoxy)benzaldehyde
CAS Number52771-21-8
Molecular FormulaC8H5F3O2
Molecular Weight190.12 g/mol
AppearanceClear liquid
Purity (GC)≥99.0%
Boiling Point83-86oC
Density1.343 g/cm3
Refractive Index1.479
Flash Point72.8oC

Industrial Applications

This fluorinated benzaldehyde derivative serves as a critical intermediate in various synthetic pathways. Its primary applications include the construction of pharmaceutical scaffolds where electron-withdrawing groups are required to modulate biological activity. Additionally, it is employed in the development of advanced agrochemicals and functional materials such as liquid crystals.

  • Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and receptor modulators.
  • Agrochemical Synthesis: Acts as a precursor for novel herbicides and fungicides.
  • Material Science: Utilized in the preparation of specialized polymers and optoelectronic materials.
  • Organic Building Block: Enables diverse chemical transformations including condensation and reduction reactions.

Quality Assurance and Safety

Every batch undergoes rigorous testing using gas chromatography (GC) and other analytical methods to confirm purity levels meet or exceed industry standards. We provide a comprehensive Certificate of Analysis (COA) with each shipment. For safety, this compound should be handled in a well-ventilated area with appropriate personal protective equipment. Storage recommendations include keeping the container tightly closed in a cool, dry, and ventilated place away from incompatible substances.

Packaging and Logistics

We offer flexible packaging solutions to meet diverse logistical requirements. Standard packing includes 200 kg drums, but custom packaging is available upon request. Our global logistics network ensures timely delivery while maintaining product integrity during transit. Contact our sales team for current bulk pricing and lead time information.