3-(Trifluoromethoxy)benzoic Acid
- CAS No.1014-81-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-(Trifluoromethoxy)benzoic acid (CAS 1014-81-9), a key fluorinated intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
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Product Overview
3-(Trifluoromethoxy)benzoic acid is a high-value fluorinated aromatic carboxylic acid widely employed as a building block in the synthesis of complex organic molecules. With its electron-withdrawing trifluoromethoxy group at the meta-position, this compound offers enhanced metabolic stability and lipophilicity—critical attributes in modern medicinal chemistry and crop protection agent design. As a specialty intermediate, it supports the development of novel active pharmaceutical ingredients (APIs) and functional materials requiring precise steric and electronic tuning.
Specifications
| Molecular Formula | C8H5F3O3 |
|---|---|
| Molecular Weight | 206.12 g/mol |
| CAS Number | 1014-81-9 |
| Appearance | White solid |
| Assay | ≥98.0% |
| Moisture | ≤0.2% |
| Melting Point | 89–92°C |
| Density | 1.447 g/cm³ |
| Boiling Point | 243.8°C |
| Flash Point | 101.2°C |
| Refractive Index | 1.477 |
Industrial Applications
This fluorinated benzoic acid derivative serves primarily as a versatile intermediate in multi-step organic syntheses. Its applications include:
- Construction of bioactive scaffolds in drug discovery programs targeting CNS disorders, oncology, and anti-infective therapies.
- Synthesis of herbicides, fungicides, and plant growth regulators in agrochemical innovation.
- Preparation of liquid crystals and specialty polymers requiring fluorine-induced thermal and chemical resistance.
Manufactured under stringent quality control protocols, our product meets international standards for research and industrial-scale use. Packaging is typically 25 kg per drum, with custom options available upon request. Store in a cool, dry, and well-ventilated area away from incompatible substances.
