Intermediates

3-Trifluoromethyl-4-bromobenzonitrile

  • CAS No.1735-53-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Trifluoromethyl-4-bromobenzonitrile (CAS 1735-53-1) for organic synthesis. Reliable supply with ≥98.0% assay.

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Product Technical Details

Product Overview

3-Trifluoromethyl-4-bromobenzonitrile is a highly specialized fluorinated organic compound that serves as a critical building block in modern chemical synthesis. This substance is characterized by the presence of both a trifluoromethyl group and a bromine substituent on the benzene ring, which significantly enhances its reactivity and utility in complex molecular constructions. Our manufacturing process ensures that every batch meets stringent quality standards, making it an ideal choice for research and industrial applications.

The incorporation of fluorine atoms into organic molecules is a cornerstone strategy in medicinal chemistry and agrochemical development. The trifluoromethyl group specifically improves metabolic stability and lipophilicity, while the bromo group provides a versatile handle for cross-coupling reactions. As a leading global manufacturer, we prioritize consistency and purity to support your downstream synthesis requirements effectively.

Key Specifications

ParameterValue
Chemical Name3-Trifluoromethyl-4-bromobenzonitrile
CAS Number1735-53-1
Molecular FormulaC8H3BrF3N
Molecular Weight250.015
AppearanceWhite to light yellow powder
Assay≥98.0%
Moisture≤0.5%
Density1.7±0.1 g/cm3
Boiling Point235.6±35.0 °C at 760 mmHg
Melting Point80-82ºC
Flash Point96.3±25.9 °C

Industrial Applications

This fluorinated intermediate is extensively utilized in the synthesis of advanced pharmaceuticals and agrochemicals. Its unique structural properties allow chemists to introduce specific functional groups with high precision. Common applications include serving as a precursor for kinase inhibitors, receptor modulators, and various biologically active compounds. The high purity level ensures minimal side reactions during synthesis, optimizing yield and reducing purification costs.

Furthermore, this compound is valuable in the development of new materials and specialty chemicals where fluorine content is required for performance enhancement. Whether used in laboratory-scale research or large-scale production, our product provides the reliability needed for successful project outcomes. We support various scales of demand, from gram quantities for R&D to tonnage for commercial manufacturing.

Storage and Handling

To maintain the integrity of 3-Trifluoromethyl-4-bromobenzonitrile, proper storage conditions are essential. The material should be kept in a cool, ventilated place away from direct sunlight and moisture. Containers must be tightly sealed to prevent contamination or degradation. Standard safety protocols for handling organic chemicals should be followed, including the use of appropriate personal protective equipment. We provide comprehensive documentation, including Certificates of Analysis (COA), to ensure full traceability and compliance with international safety standards.