3-Trifluoromethylbenzoic Acid
- CAS No.454-92-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Trifluoromethylbenzoic Acid (CAS 454-92-2) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediate manufacturing.
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Product Overview
3-Trifluoromethylbenzoic Acid represents a critical fluorinated building block within the realm of modern organic chemistry. As a derivative of benzoic acid featuring a trifluoromethyl substituent at the meta position, this compound offers unique electronic and steric properties that are highly sought after in complex molecular construction. The presence of the strong electron-withdrawing trifluoromethyl group significantly influences the reactivity of the aromatic ring, making it an indispensable precursor for various downstream chemical transformations.
Our manufacturing facility produces this intermediate under strict quality control protocols to ensure consistent batch-to-batch reproducibility. The compound is characterized by its stability under standard storage conditions and its compatibility with a wide range of synthetic reactions. Whether utilized in medicinal chemistry programs or agrochemical development, this material provides a reliable foundation for introducing fluorine motifs into target molecules.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Trifluoromethylbenzoic Acid |
| CAS Number | 454-92-2 |
| Molecular Formula | C8H5F3O2 |
| Molecular Weight | 190.12 g/mol |
| Appearance | Off-white to white crystalline powder |
| Purity (HPLC) | ≥99.0% |
| Melting Point | 104-106°C |
| Boiling Point | 238.5°C |
| Density | 1.403 g/cm³ |
Industrial Applications
This fluorinated intermediate serves as a versatile substrate in the synthesis of pharmaceutical agents, agrochemicals, and advanced materials. The trifluoromethyl group is known to enhance metabolic stability and lipophilicity in drug candidates, making this acid a valuable tool for medicinal chemists. It is frequently employed in cross-coupling reactions, amidation processes, and esterification protocols to generate more complex molecular architectures.
Key application areas include:
- Pharmaceutical intermediate synthesis for novel drug discovery programs.
- Agrochemical formulation development requiring enhanced environmental stability.
- Production of liquid crystals and functional polymeric materials.
- Research and development in organofluorine chemistry laboratories.
Quality Assurance and Logistics
We understand that purity and consistency are paramount in chemical manufacturing. Every batch of 3-Trifluoromethylbenzoic Acid undergoes rigorous analytical testing, including HPLC analysis, to verify compliance with specified purity levels. A comprehensive Certificate of Analysis (COA) is provided with each shipment to ensure full traceability and quality assurance.
Our logistics network supports global distribution with appropriate packaging to maintain product integrity during transit. Standard packaging includes 25 kg drums, though we offer flexible custom packaging solutions to meet specific client requirements. Storage recommendations include keeping the material in a cool, ventilated place away from incompatible substances to preserve its chemical properties over extended periods.
