Intermediates

3H-1,3,4-Thiadiazole-2-Thione

  • CAS No.18686-82-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3H-1,3,4-Thiadiazole-2-Thione (CAS 18686-82-3) designed for pharmaceutical synthesis. Ideal intermediate for Ceftezole production with ≥98.0% purity assurance.

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Product Technical Details

Product Overview

3H-1,3,4-Thiadiazole-2-Thione represents a critical heterocyclic building block within the modern pharmaceutical industry. This specialized chemical compound is characterized by its unique thiadiazole ring structure, which imparts significant stability and reactivity suitable for complex organic synthesis. As a key intermediate, it serves as a foundational element in the construction of various therapeutic agents, particularly within the cephalosporin antibiotic class. Our manufacturing process ensures that every batch meets rigorous international standards for chemical purity and consistency.

The compound is extensively utilized in the development of advanced medicinal formulations. Its chemical properties allow for versatile functionalization, making it an indispensable resource for research laboratories and large-scale production facilities alike. By securing a reliable supply of this high-grade intermediate, pharmaceutical companies can streamline their synthesis workflows and maintain optimal production timelines for essential medications.

Specifications and Physical Properties

ParameterValue
CAS Number18686-82-3
Molecular FormulaC2H2N2S2
Molecular Weight118.18 g/mol
AppearanceWhite to pale yellow solid
Purity≥98.0%
Melting Point142-144°C
Density1.73 g/cm³
Boiling Point176°C

Industrial Applications

The primary application of 3H-1,3,4-Thiadiazole-2-Thione lies in the synthesis of Ceftezole, a potent cephalosporin antibiotic. The thiadiazole moiety is crucial for the biological activity and pharmacokinetic profile of the final drug product. Beyond antibiotic synthesis, this chemical finds utility in the creation of other heterocyclic derivatives used in agrochemicals and specialized material science. Our team works closely with clients to understand specific formulation requirements, ensuring the material provided aligns perfectly with downstream processing needs.

  • Essential precursor for cephalosporin antibiotic manufacturing
  • High reactivity for efficient organic synthesis routes
  • Consistent quality for reproducible laboratory results
  • Compatible with various standard chemical reaction conditions
  • Supported by comprehensive technical documentation

Quality Assurance and Storage

Quality control is paramount in our production facility. Each lot undergoes strict analytical testing using advanced chromatography and spectroscopy methods to verify identity and purity levels. We provide a Certificate of Analysis (COA) with every shipment, guaranteeing transparency and compliance with regulatory expectations. Proper storage is essential to maintain the integrity of the product. It should be kept in a cool, ventilated area away from direct sunlight and moisture. Packaging is available in 25 kg drums, with customization options to suit specific logistical requirements. By choosing our facility, you partner with a global manufacturer committed to safety, reliability, and excellence in chemical supply.