(3R,4S)-3-Hydroxy-4-phenylazetidin-2-one

Product Overview

(3R,4S)-3-Hydroxy-4-phenylazetidin-2-one is a high-value, enantiomerically pure β-lactam derivative widely employed as a critical building block in the synthesis of complex therapeutic agents. With a defined stereochemistry at the 3R and 4S positions, this compound serves as an essential intermediate in the development of next-generation anticancer molecules, particularly in taxane-based drug scaffolds.

Specifications

Quality Control & Analytical Data

Our product meets stringent quality benchmarks for use in regulated pharmaceutical manufacturing environments. Each batch undergoes comprehensive analytical validation to ensure consistency and reliability.

• Appearance: Off-white to white powder
• Assay (HPLC): 99.1% (specification: 97.0–102.0%)
• Total Impurities: ≤0.86% (limit: ≤2.0%)
• Water Content: 0.24% (limit: ≤0.5%)
• Residual Solvents (Ethyl Acetate): 0.22% (limit: ≤0.5%)
• Identification Confirmed by NMR Spectroscopy

Industrial Applications

This chiral azetidinone functions exclusively as a synthetic intermediate in multi-step organic routes toward potent oncology therapeutics. It is not intended for direct therapeutic, cosmetic, or nutraceutical use. Its rigid β-lactam core and phenyl substitution pattern enable precise stereochemical control during downstream coupling reactions, making it invaluable in the construction of complex molecular architectures under GMP-compliant processes.

Storage: Keep in a cool, dry, and well-ventilated area. Packaging: Standard 25 kg fiber drums; custom packaging available upon request.