Intermediates

4-(3-Chloropropyl)morpholine

  • CAS No.7357-67-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-(3-Chloropropyl)morpholine liquid designed for pharmaceutical synthesis. Reliable supply for Gefitinib intermediate production with strict quality control.

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Product Technical Details

Product Overview

4-(3-Chloropropyl)morpholine is a specialized organic compound widely recognized for its pivotal role in advanced pharmaceutical synthesis. As a key morpholine derivative, this chemical serves as an essential building block in the production of complex therapeutic agents, including notable intermediates for oncology treatments such as Gefitinib. Our manufacturing process ensures that every batch meets rigorous international standards, providing clients with a reliable source of high-performance chemical raw materials. The compound is characterized by its stability and reactivity, making it an ideal candidate for nucleophilic substitution reactions in multi-step synthesis routes.

Technical Specifications

ParameterValue
CAS Number7357-67-7
Molecular FormulaC7H14ClNO
Molecular Weight163.65 g/mol
AppearanceColorless to light yellow clear liquid
Purity (GC)≥98.0%
Density1.062 g/cm3
Boiling Point227.1°C
Melting Point-52°C
Flash Point67°C
Moisture Content≤0.5%

Industrial Applications

The primary application of 4-(3-Chloropropyl)morpholine lies within the pharmaceutical industry, specifically as a critical intermediate in the synthesis of tyrosine kinase inhibitors. Its chemical structure allows for efficient coupling reactions, facilitating the construction of complex molecular architectures required for modern medicine. Beyond pharmaceuticals, this morpholine derivative may find utility in fine chemical synthesis where specific alkylating agents are required. Our product is engineered to support scalable manufacturing processes, ensuring consistency from laboratory research to full-scale commercial production. Clients utilizing this material benefit from optimized reaction yields and reduced impurity profiles in downstream processes.

Quality Assurance and Storage

We maintain a comprehensive quality management system to guarantee the integrity of 4-(3-Chloropropyl)morpholine. Each shipment is accompanied by a Certificate of Analysis (COA) verifying purity levels, impurity limits, and physical properties. To maintain optimal stability, the product should be stored in a cool, ventilated area away from direct sunlight and moisture sources. Proper handling protocols are recommended due to the chemical nature of the substance, including the use of appropriate personal protective equipment during transfer operations. Our packaging options include 200 kg drums, with flexibility to accommodate specific customer logistical requirements for global distribution.

Why Choose Our Supply

  • Consistent industrial purity levels exceeding 98 percent.
  • Robust supply chain capable of supporting bulk orders.
  • Technical support for synthesis route optimization.
  • Compliance with international safety and shipping regulations.
  • Competitive bulk pricing for long-term partnerships.