4-(1-Acetylpiperazin-4-yl)Phenol
- CAS No.67914-60-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-(1-Acetylpiperazin-4-yl)Phenol (CAS 67914-60-7) supplied as a white powder for pharmaceutical synthesis. Ideal for large-scale industrial applications with full documentation.
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Product Overview
4-(1-Acetylpiperazin-4-yl)Phenol is a sophisticated organic compound widely recognized for its critical role in the synthesis of advanced pharmaceutical agents. As a key building block in fine chemistry, this substance features a unique structural combination of a piperazine ring and a phenolic group, making it highly valuable for medicinal chemistry applications. Our facility specializes in the production of this high-quality intermediate, ensuring that every batch meets stringent international standards for purity and consistency. We understand the demands of modern drug discovery and development, which is why our manufacturing processes are designed to deliver reliable materials for complex synthetic routes.
This chemical entity serves as a fundamental precursor in the production of various therapeutic compounds, particularly within the antifungal category. The structural integrity of the acetylpiperazine moiety allows for versatile chemical modifications, enabling chemists to develop novel derivatives with enhanced biological activity. Our commitment to excellence ensures that researchers and industrial partners receive a product that facilitates efficient synthesis workflows without compromising on quality or safety.
Technical Specifications
To guarantee optimal performance in downstream applications, we maintain rigorous control over the physical and chemical properties of 4-(1-Acetylpiperazin-4-yl)Phenol. Each production lot undergoes comprehensive analysis using state-of-the-art instrumentation, including High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy. The following table outlines the standard specifications for our commercial grade material:
| Parameter | Specification |
|---|---|
| Chemical Name | 4-(1-Acetylpiperazin-4-yl)Phenol |
| CAS Registry Number | 67914-60-7 |
| Molecular Formula | C12H16N2O2 |
| Molecular Weight | 220.27 g/mol |
| Appearance | White Powder |
| Purity (HPLC) | ≥98.0% |
| Melting Point | 180-185 °C |
| Density | 1.207 g/cm3 |
| Boiling Point | 456.5 °C at 760 mmHg |
Industrial Applications
The primary application of this compound lies in the pharmaceutical industry, where it acts as a vital intermediate for the synthesis of antifungal medications. Specifically, it is utilized in the manufacturing process of Ketoconazole and related therapeutic agents. The high purity level of our product ensures minimal impurity carryover into the final Active Pharmaceutical Ingredient (API), which is crucial for regulatory compliance and patient safety. Beyond antifungal drugs, the versatile reactivity of the phenol and piperazine groups allows for its use in developing other neurological and systemic therapeutics.
Our clients benefit from a stable supply chain that supports both research-scale experiments and large-scale commercial production. Whether you are optimizing a synthesis route or scaling up for industrial manufacturing, our material provides the consistency required for reproducible results. We work closely with process chemists to understand specific requirements, offering customization options for packaging and purity levels to match distinct project needs.
Storage and Handling
Proper storage conditions are essential to maintain the stability and quality of 4-(1-Acetylpiperazin-4-yl)Phenol over time. The product should be stored in a cool, dry environment, ideally in a freezer at -20°C for long-term preservation. Containers must be well-closed to protect the material from moisture, strong light, and heat, which could degrade the chemical structure. When handling this substance, standard laboratory safety protocols should be followed, including the use of appropriate personal protective equipment such as gloves and safety goggles.
We package our products in 25kg cardboard drums or according to specific customer requirements to ensure safe transportation globally. Each shipment is accompanied by a Certificate of Analysis (COA) and relevant safety data sheets. Our logistics team ensures that all regulatory guidelines for chemical transport are met, providing peace of mind for international buyers. For bulk pricing inquiries or technical support regarding synthesis applications, our expert team is available to assist you in optimizing your procurement strategy.
