Intermediates

4,4,4-Trifluoro-1-(4-methylphenyl)butane-1,3-dione

  • CAS No.720-94-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4,4,4-Trifluoro-1-(4-methylphenyl)butane-1,3-dione (CAS 720-94-5) designed for pharmaceutical synthesis. Available in bulk quantities with comprehensive quality documentation.

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Product Technical Details

Product Overview

4,4,4-Trifluoro-1-(4-methylphenyl)butane-1,3-dione is a specialized fluorinated organic compound serving as a critical building block in modern medicinal chemistry. This advanced chemical intermediate features a unique trifluoromethyl ketone structure that enhances metabolic stability and bioavailability in downstream pharmaceutical applications. Our manufacturing process ensures exceptional purity levels, making it an ideal candidate for complex organic synthesis routes required in the development of novel therapeutic agents.

As a leading global manufacturer, we understand the stringent requirements of the pharmaceutical industry. This product is synthesized under strictly controlled conditions to minimize impurities and ensure batch-to-batch consistency. The incorporation of fluorine atoms into the molecular backbone provides distinct chemical properties that are highly valued in the design of active pharmaceutical ingredients (APIs), particularly those targeting inflammatory pathways and enzyme inhibition.

Technical Specifications

We adhere to rigorous quality control standards to guarantee that every shipment meets the specified physical and chemical parameters. The following table outlines the key technical data for this compound, verified through advanced analytical methods including HPLC and NMR spectroscopy.

ParameterValue
CAS Number720-94-5
Molecular FormulaC11H9F3O2
Molecular Weight230.183 g/mol
AppearanceLight yellow crystalline powder
Assay (Purity)≥98.0%
Melting Point44-46 °C
Boiling Point269.9±35.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point94.1±22.8 °C

Industrial Applications

This fluorinated dione is primarily utilized as a key intermediate in the synthesis of pharmaceutical compounds. Its structural characteristics make it particularly suitable for reactions involving enolization and condensation, which are fundamental steps in constructing heterocyclic systems found in many modern drugs.

  • Pharmaceutical Intermediate: Used in the synthesis of anti-inflammatory agents and COX-2 inhibitors.
  • Organic Synthesis: Serves as a versatile reagent for introducing trifluoromethyl groups into complex molecules.
  • Research and Development: Employed in laboratory settings for exploring new chemical entities and structure-activity relationships.
  • Custom Manufacturing: Available for tailored synthesis projects requiring specific purity profiles or particle size distributions.

Quality Assurance and Logistics

Quality is the cornerstone of our operation. Each batch of 4,4,4-Trifluoro-1-(4-methylphenyl)butane-1,3-dione is accompanied by a comprehensive Certificate of Analysis (COA) detailing all test results. We maintain full traceability from raw material sourcing to final packaging, ensuring compliance with international chemical safety standards.

For logistics, we offer flexible packaging solutions to meet diverse customer needs. Standard packaging includes 25 kg drums, which are designed to protect the product from moisture and light during transit. However, we can accommodate custom packaging requirements upon request. Storage recommendations include keeping the material in a cool, ventilated place away from incompatible substances. Our global shipping network ensures timely delivery to research facilities and manufacturing plants worldwide, supported by responsive customer service for any technical inquiries.