4,5-Bis(2-methoxyethoxy)-2-nitrobenzonitrile

Product Overview

4,5-Bis(2-methoxyethoxy)-2-nitrobenzonitrile is a specialized organic compound primarily utilized within the pharmaceutical industry as a critical building block. This chemical substance serves as a key intermediate in the multi-step synthesis of kinase inhibitors, specifically contributing to the production of Erlotinib hydrochloride. Our facility ensures that every batch meets rigorous international standards for medicinal chemistry applications, providing researchers and manufacturers with a reliable source of high-quality raw materials.

As a nitrile derivative featuring methoxyethoxy substituents, this compound exhibits specific reactivity profiles essential for constructing complex heterocyclic frameworks found in modern oncology therapeutics. The precise molecular architecture allows for efficient downstream functionalization, making it a preferred choice for process chemistry teams aiming to optimize yield and purity in API manufacturing.

Technical Specifications

Industrial Applications

The primary application of this material lies in the pharmaceutical sector, where it acts as a precursor for Erlotinib hydrochloride. Erlotinib is a well-known epidermal growth factor receptor (EGFR) inhibitor used in the treatment of various forms of cancer. Consequently, the quality of this intermediate directly impacts the safety and efficacy of the final drug product. Our manufacturing process is designed to minimize impurities that could complicate subsequent reaction steps or affect the crystallization properties of the final active pharmaceutical ingredient.

Beyond its specific role in oncology drug synthesis, this benzonitrile derivative is also valuable for research and development purposes involving nitro-aromatic chemistry. Laboratories focusing on medicinal chemistry often require such specialized intermediates to explore new analogues or improve existing synthetic routes. We support both large-scale commercial production and smaller-scale R&D initiatives with flexible ordering options.

Quality Assurance and Safety

Quality control is paramount in the production of pharmaceutical intermediates. Each batch of 4,5-Bis(2-methoxyethoxy)-2-nitrobenzonitrile undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify structural integrity and purity levels. A Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with customer specifications. We adhere to strict safety protocols during handling and packaging to maintain product stability.

Regarding safety, this compound should be handled in accordance with standard laboratory safety practices for organic nitro compounds. Proper personal protective equipment (PPE) is recommended during handling to prevent inhalation or skin contact. Our safety data sheets (SDS) are available upon request to guide safe storage and usage within your facility.

Packaging and Logistics

We understand the importance of secure packaging for chemical shipments. The standard packing configuration is 25kg cardboard drums, which offer excellent protection against moisture and physical damage during transit. Custom packaging solutions are available to meet specific logistical requirements or bulk ordering needs. Our logistics network supports global shipping, ensuring timely delivery to manufacturing sites worldwide while maintaining the integrity of the chemical product throughout the supply chain.

Storage recommendations include keeping the container tightly closed in a cool, dry, and well-ventilated area. Avoiding exposure to direct sunlight and incompatible materials ensures the long-term stability of the powder. For further technical inquiries or to request a sample, please contact our sales team for prompt assistance and competitive bulk pricing.