Intermediates

4,5-Difluoro-2-methoxybenzonitrile

  • CAS No.425702-28-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4,5-Difluoro-2-methoxybenzonitrile designed for advanced organic synthesis and pharmaceutical intermediate applications with reliable quality assurance.

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Product Technical Details

Product Overview

4,5-Difluoro-2-methoxybenzonitrile is a specialized fluorinated aromatic compound widely recognized for its utility in modern medicinal chemistry and advanced organic synthesis. As a key building block, this nitrile derivative facilitates the construction of complex molecular architectures required in the development of novel pharmaceutical agents and agrochemical products. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial scale applications.

The presence of fluorine atoms at the 4 and 5 positions enhances the metabolic stability and lipophilicity of downstream molecules, making this intermediate highly valuable for drug discovery programs. The methoxy group further provides versatile handles for subsequent chemical transformations. We maintain strict quality control protocols to guarantee that every batch meets rigorous international standards for chemical intermediates.

Key Specifications

Our production facility adheres to Good Manufacturing Practices to deliver products with reliable physical and chemical properties. The following table outlines the critical technical parameters for this compound.

ParameterValue
CAS Number425702-28-9
Molecular FormulaC8H5F2NO
Molecular Weight169.128
AppearanceWhite to light yellow powder
Assay≥98.0%
Melting Point89-90°C
Boiling Point251.1±35.0 °C at 760 mmHg
Density1.3±0.1 g/cm3

Industrial Applications

This fluorinated benzonitrile derivative serves as a critical precursor in the synthesis of kinase inhibitors and other therapeutic compounds. Its robust chemical structure allows for various substitution reactions, enabling chemists to introduce diverse functional groups efficiently. Beyond pharmaceuticals, it finds application in the development of advanced materials and specialized agrochemical formulations where fluorine substitution is required to enhance performance characteristics.

  • Pharmaceutical intermediate for targeted therapy development
  • Building block for fluorinated organic compounds
  • Reagent for medicinal chemistry research
  • Precursor for agrochemical active ingredients

Quality Assurance And Handling

We provide a comprehensive Certificate of Analysis with every shipment to verify purity and identity. Our logistics network ensures safe and timely global delivery. For storage, keep the container tightly closed in a cool, ventilated area away from incompatible substances. Proper handling procedures should be followed to maintain product integrity throughout its shelf life. Contact our technical sales team for detailed safety data sheets and custom packaging options tailored to your specific production needs.