4,5-Difluoro-2-nitrobenzoic Acid

Product Overview

4,5-Difluoro-2-nitrobenzoic Acid is a specialized fluorinated aromatic intermediate widely utilized in the field of advanced organic synthesis. As a key building block, this compound plays a critical role in the development of pharmaceutical agents, agrochemicals, and functional materials. Our manufacturing process ensures consistent quality and high purity, making it an ideal choice for research and industrial scale production.

The presence of both fluoro and nitro functional groups on the benzoic acid scaffold provides unique reactivity profiles, allowing for diverse chemical transformations. This versatility makes it a preferred candidate for medicinal chemistry programs aiming to introduce fluorine atoms into complex molecular structures to enhance metabolic stability and bioavailability.

Key Specifications

Physical and Chemical Properties

This compound exhibits robust physical properties suitable for various reaction conditions. With a melting point ranging between 165 and 167 degrees Celsius, it demonstrates thermal stability during storage and handling. The molecular weight of 203.100 g/mol facilitates precise stoichiometric calculations in synthesis protocols.

The density is approximately 1.7 g/cm3, and the compound shows low vapor pressure at room temperature, ensuring safe handling in standard laboratory environments. The boiling point is recorded at 349.7 degrees Celsius under standard atmospheric pressure, indicating high thermal resistance. These characteristics contribute to its reliability as a starting material in multi-step synthesis routes.

Industrial Applications

Primarily used as an intermediate in organic synthesis, 4,5-Difluoro-2-nitrobenzoic Acid serves as a precursor for numerous downstream chemicals. In the pharmaceutical industry, it is employed in the construction of kinase inhibitors and other targeted therapies where fluorine substitution is crucial for drug efficacy.

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Development: Serves as a building block for novel pesticides and herbicides.
• Material Science: Utilized in the creation of specialized polymers and liquid crystals.
• Research and Development: Essential for academic and industrial labs focusing on fluorination chemistry.

Packaging and Storage

To maintain product integrity, we offer flexible packaging options tailored to client needs. The standard package is 25 kg per drum, ensuring secure transport for bulk orders. Custom packaging solutions are available upon request to accommodate specific logistical requirements.

Storage recommendations include keeping the material in a cool, ventilated place away from direct sunlight and moisture. Proper sealing is essential to prevent hydration or contamination. When handled according to safety guidelines, this product remains stable for extended periods, supporting long-term project planning.

Quality Assurance and Support

Our commitment to quality is underscored by rigorous testing protocols. Each batch is accompanied by a Certificate of Analysis (COA) verifying purity and physical constants. We provide comprehensive technical support to assist with integration into your manufacturing processes, ensuring seamless adoption and optimal results.