4,5-Dimethyl-1,3-dioxol-2-one
- CAS No.37830-90-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 4,5-Dimethyl-1,3-dioxol-2-one serving as a critical pharmaceutical intermediate for Olmesartan synthesis. Available in bulk quantities with full quality documentation.
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Product Overview
4,5-Dimethyl-1,3-dioxol-2-one, frequently recognized in industrial contexts as Dimethylvinylene carbonate, represents a specialized organic compound essential to modern pharmaceutical manufacturing. This cyclic carbonate derivative serves as a vital building block in the synthesis of complex therapeutic agents, particularly within the angiotensin II receptor blocker class. Our facility produces this material under strict quality control protocols to ensure consistency and reliability for downstream chemical processes.
As a key intermediate, this compound facilitates specific structural modifications required during multi-step organic synthesis. Its chemical stability and reactivity profile make it an preferred choice for manufacturers seeking efficient routes to high-value active pharmaceutical ingredients. We maintain robust production capabilities to support global supply chains with timely deliveries and competitive commercial terms.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 37830-90-3 |
| Molecular Formula | C5H6O3 |
| Molecular Weight | 114.10 g/mol |
| Purity | ≥99.0% |
| Melting Point | 78°C |
| Boiling Point | 130°C at 760 mmHg |
| Density | 1.2 ± 0.1 g/cm3 |
| Loss on Drying | ≤0.3% |
Industrial Applications
The primary application of 4,5-Dimethyl-1,3-dioxol-2-one lies in the pharmaceutical sector, specifically as a precursor in the manufacturing of Olmesartan medoxomil. This antihypertensive agent requires precise intermediate chemistry to achieve the necessary stereochemistry and functional group placement. Our product is engineered to meet the rigorous demands of medicinal chemistry teams focusing on cardiovascular therapeutics.
Beyond specific drug synthesis, this chemical finds utility in broader organic synthesis projects where cyclic carbonate structures are required. Researchers utilize this material for developing new synthetic routes, optimizing reaction yields, and scaling up processes from laboratory to industrial production. The high purity grade ensures minimal side reactions and simplified purification steps.
Quality Assurance
Quality is paramount in pharmaceutical intermediate supply. Every batch undergoes comprehensive testing using advanced analytical techniques including HPLC, GC, and NMR spectroscopy. We provide a Certificate of Analysis with each shipment, detailing all critical quality attributes and confirming compliance with specified standards. Our quality management system aligns with international best practices to guarantee product safety and efficacy.
- Strict raw material sourcing and vendor qualification
- In-process controls at every manufacturing stage
- Final product verification against master specifications
- Stability testing to ensure shelf-life integrity
Storage and Handling
To maintain optimal chemical stability, 4,5-Dimethyl-1,3-dioxol-2-one should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly closed to prevent moisture absorption and exposure to strong light or heat sources. Standard industrial safety precautions apply during handling, including the use of appropriate personal protective equipment. Proper storage conditions ensure the material retains its specified purity and physical characteristics throughout its shelf life.
