Intermediates

4-(6,7-Dimethoxyquinolin-4-yl)oxyaniline

  • CAS No.190728-25-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4-(6,7-Dimethoxyquinolin-4-yl)oxyaniline serves as a critical intermediate for Cabozantinib synthesis. We offer bulk supply with full COA and custom packaging options for global pharmaceutical partners.

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Product Technical Details

Product Overview

4-(6,7-Dimethoxyquinolin-4-yl)oxyaniline is a specialized organic compound primarily utilized in the pharmaceutical industry as a key building block for the synthesis of kinase inhibitors. This high-value intermediate plays a pivotal role in the manufacturing process of Cabozantinib, a potent multi-kinase inhibitor used in oncology treatments. Our facility ensures that every batch meets rigorous international standards for purity and consistency, supporting the development of life-saving therapies.

As a leading global manufacturer, we understand the critical nature of supply chain reliability in drug development. Our production capabilities are designed to scale from laboratory research quantities to large-scale commercial manufacturing, ensuring seamless support for our partners at every stage of their pipeline.

Technical Specifications

ParameterValue
Chemical Name4-(6,7-Dimethoxyquinolin-4-yl)oxyaniline
CAS Number190728-25-7
Molecular FormulaC17H16N2O3
Molecular Weight296.32 g/mol
AppearanceWhite powder
Purity (HPLC)≥98.0%
Packaging25 kg/drum or custom

Industrial Applications

This compound is specifically engineered for use in the synthesis of advanced pharmaceutical APIs. Its primary application lies in the construction of the quinoline core structure found in Cabozantinib, which targets receptors involved in tumor growth and angiogenesis. The high purity level ensures minimal impurity profiles in the final drug substance, facilitating smoother regulatory approval processes.

  • Essential intermediate for Cabozantinib production
  • Used in kinase inhibitor research and development
  • Supports oncology therapeutic manufacturing
  • Compatible with standard organic synthesis routes

Quality Assurance and Storage

Quality is the cornerstone of our manufacturing philosophy. Each batch of 4-(6,7-Dimethoxyquinolin-4-yl)oxyaniline undergoes comprehensive testing using high-performance liquid chromatography (HPLC) to verify purity levels. We provide a Certificate of Analysis (COA) with every shipment, detailing all relevant quality parameters. Our facilities adhere to strict safety and environmental protocols to ensure product integrity.

For optimal stability, the product should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper storage conditions maintain the chemical stability and potency of the material over extended periods. We offer flexible packaging solutions, including 25 kg drums, and can accommodate specific customer requirements to align with your logistics and handling protocols. Contact our technical sales team for detailed specifications and bulk pricing inquiries.