Intermediates

4-[(6-oxo-1H-pyrimidin-2-yl)amino]benzonitrile

  • CAS No.189956-45-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of antiretroviral agents. Available in bulk quantities with strict quality control.

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Product Technical Details

Product Overview

4-[(6-oxo-1H-pyrimidin-2-yl)amino]benzonitrile is a specialized organic compound recognized for its critical role in modern medicinal chemistry. As a key pyrimidine derivative, this substance serves as an essential building block in the production of advanced pharmaceutical active ingredients. Our facility ensures that every batch meets rigorous international standards, providing reliability for downstream synthesis processes. The compound is characterized by its stable chemical structure and high reactivity, making it ideal for complex organic transformations required in API manufacturing.

We understand the importance of consistency in pharmaceutical supply chains. Therefore, our production processes are designed to minimize impurities and maximize yield. This product is particularly valued in the development of antiretroviral therapies, where precision and purity are paramount. By sourcing from a dedicated manufacturer, clients gain access to technical support and consistent supply availability.

Technical Specifications

The following table outlines the key physical and chemical properties of this intermediate. These parameters are verified through advanced analytical methods to ensure compliance with specified requirements.

ParameterValue
CAS Number189956-45-4
Molecular FormulaC11H8N4O
Molecular Weight212.207
AppearanceWhite to yellow powder
Assay≥98.0%
Density1.4±0.1 g/cm3
Boiling Point482.3±51.0 °C at 760 mmHg
Flash Point245.5±30.4 °C

Industrial Applications

This chemical intermediate is primarily utilized in the synthesis of Rilpivirine, a notable antiretroviral medication. Its function as a precursor allows for the construction of complex molecular architectures necessary for therapeutic efficacy. Beyond this specific application, the compound serves as a versatile component in various research and development projects focused on heterocyclic chemistry. Laboratories and production facilities rely on this material for its predictable performance in coupling reactions and structural modifications.

  • Essential precursor for antiretroviral API synthesis
  • High stability under standard storage conditions
  • Compatible with diverse organic synthesis routes
  • Supports large-scale manufacturing requirements

Quality Assurance and Packaging

Quality control is integral to our operation. Each production lot undergoes comprehensive testing to verify identity, purity, and physical characteristics. We provide a Certificate of Analysis (COA) with every shipment to document compliance. The product is packaged in secure 25 kg drums, though custom packaging solutions are available to meet specific logistical needs. Proper storage in a cool, ventilated environment ensures the material maintains its integrity over time. Our commitment to safety and quality makes us a preferred partner for global pharmaceutical manufacturers seeking reliable intermediate supplies.